DDX6

DDX6

A gene on chromosome 11q23.3 that encodes a putative RNA helicase with a conserved Asp-Glu-Ala-Asp (DEAD) motif which is found in P-bodies and stress granules. It suppresses translation and mRNA degradation, and is required for microRNA-induced gene silencing.
References in periodicals archive ?
Genome-wide association studies have identified several genetic loci associated with increased risk of glioma, including TERT, CDKN2A/2B, RTEL1, PHLDB1, EGFR, TP53, TERC, DDX6, and PIWI-interacting RNAs.
3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.
research has indicated that the interaction between DDX6 and the 11-kDa
DDX6 encodes a member of the DEAD box protein family, which has multiple functions including translation suppression and mRNA degradation (Weston and Sommerville, 2006).
DETERMINATION OF THE BINDING SITE OF ADENOVIRUS E4 ORF3 AND DDX6 **, Julia A.