DDX20 | definition of DDX20 by Medical dictionary
DDX20 A gene on chromosome 1p21.1-p13.2 that encodes a protein which has a conserved Asp-Glu-Ala-Asp (DEAD) motif and is an ATP-dependent RNA helicase belonging to the SMN complex, which plays a key role in spliceosomal snRNP assembly in the cytoplasm. The complex is required for pre-mRNA splicing in the nucleus and may play a role in snoRNP metabolism.
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References in periodicals archive
DEAD box RNA helicase 20 (DDX20
), forkhead transcription factor 2 (FOXL2), and fushi tarazu factor 1 (FTZ-F1) were investigated in the regulation of vitellogenesis (VTG).
This duplex is then loaded into the miRISC, which includes an AGO2 protein, GW182/TNRC6 proteins, Gemin 3/4 (Deadbox helicases DDX20
and DDX42), among other potential proteins, and the mature functional guide single-stranded miRNA yielding a functional miRISC.