DDX17

DDX17

A gene on chromosome 22q13.1 that encodes a protein which has a conserved Asp-Glu-Ala-Asp (DEAD) motif and has RNA-dependent ATPase activity.
References in periodicals archive ?
Some transcription factors, such as p53, receptor-regulated SMADs (R-Smads), and estrogen receptor a (ER[alpha]), can also participate in the rapid regulation of miRNA expression in response to extracellular stimuli by interacting with the DEAD-box RNA helicases p68 (DDX5) and/or p72 (DDX17).
The microprocessor complex also contains a variety of cofactors including the DEAD box (amino acid sequence D-E-A-D asp-glu-ala-asp) RNA helicases p68 (DDX5) and p72 (DDX17), as well as heterogeneous nuclear ribonucleoproteins (hnRNPs) [11,12].