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a platinum coordination compound whose main mode of action resembles that of alkylating agents with production of cross links between the two strands of DNA in the double helix so that DNA cannot be replicated and the cells cannot divide. It is used as an antineoplastic agent in the treatment of metastatic tumors of the testis, ovary, bladder, and head and neck. It can cause serious damage to the kidney, eighth cranial nerve, gastrointestinal tract, and bone marrow, can upset metabolic processes, and can produce hypocalcemia and hypomagnesemia. Called also DDP or cis-DDP.


Notation for the gene for DFN1.



cis- DDP



Mohr-Tranebjaerg syndrome

An autosomal recessive neurodegenerative syndrome (OMIM:304700) characterised by postlingual progressive sensorineural deafness as the first presenting symptom in early childhood, followed by progressive dystonia, spasticity, dysphagia, mental deterioration and cortical blindness.

Molecular pathology
Defects of TIMM8A, which encodes a translocase, cause Mohr-Tranebjaerg syndrome.


diaminedichloroplatinum, a heavy metal complex; used as an antineoplastic agent. See also cisplatin.

Patient discussion about DDP

Q. Is pervasive developmental disorder (PDD) or autism is fatal……what exactly it is……?

A. Autism is not fatal in its symptom and progression but it can become fatal as it does impair normal physiological function it CAN BE a fatal condition. It’s a group of illness which involves delays in the development of basic skills. It happens to children below age 3. It affects the child`s ability to communicate and interact. Autism affected children are also found to be mentally retarded.

Q. I was at my colleague's home and one of his kids kept talking to herself he said that she has PDD. i later asked my wife about it and she said she thinks it's a type of autism. but other than talking to herself the girl seemed perfectly normal. so is PDD a light version of autism?

A. I didn't really understand everything in this web page, but I think I get the big picture. Thanx

Q. What resources are available in Seattle, Washington to help with an autistic child?

A. i miss Seattle... here is a link to "Autism Spectrum Treatment and Research (ASTAR) Center". a well know establishment:


More discussions about DDP
References in periodicals archive ?
In addition to the DDPs, employment case law and ACAS guidance requires employer to also do the following:
The final list and recommendations will be presented to the DDP at the July 15th briefing.
No, there is a modified DDP which can be used in cases of alleged 'gross misconduct'.
PDF Enhancer delivers both," affirms Charlie Barranco, Director of Implementation and Customer Service at DDP.
CFC is the largest film studio in China and boasts incomparable experience and capacity for all aspects of film production, project development and resource consolidation," said Wilson Qiu, Chairman and CEO of DDP.
Lot 3 312 530 lev (three hundred and twelve thousand five hundred and thirty lev), excluding VAT, including price for making DDP - 4930 (four thousand nine hundred thirty lev), not incl.
The rating affirmations of DDP and DDNY reflect their affiliation with Dentegra Group, Inc.
4, 2014 /PRNewswire/ -- ScaleArc today announced that DDP YOGA has selected ScaleArc to ensure the availability and performance of its website.
CrimeCog and DDP join forces to link police records for nearly 1/3 of the police agencies in Michigan
Patel has also informed that the Centre offers funding of as much as 90% in DPAP areas, while DDP areas are entitled for just 25% of funds in line with the AIBP guidelines.
His DDP yoga series has had worldwide appeal, which has led to healthier lifestyles.
Recognized as a worldwide leader in media manufacturing solutions, DCA presented the industry with a great many firsts, including real-time mastering, CD-ROM mastering, CAV mastering, DDP, the first DVD end-to-end glass mastering solution, and bit-to-bit verification for optical media.