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a platinum coordination compound whose main mode of action resembles that of alkylating agents with production of cross links between the two strands of DNA in the double helix so that DNA cannot be replicated and the cells cannot divide. It is used as an antineoplastic agent in the treatment of metastatic tumors of the testis, ovary, bladder, and head and neck. It can cause serious damage to the kidney, eighth cranial nerve, gastrointestinal tract, and bone marrow, can upset metabolic processes, and can produce hypocalcemia and hypomagnesemia. Called also DDP or cis-DDP.


Notation for the gene for DFN1.



cis- DDP



Mohr-Tranebjaerg syndrome

An autosomal recessive neurodegenerative syndrome (OMIM:304700) characterised by postlingual progressive sensorineural deafness as the first presenting symptom in early childhood, followed by progressive dystonia, spasticity, dysphagia, mental deterioration and cortical blindness.

Molecular pathology
Defects of TIMM8A, which encodes a translocase, cause Mohr-Tranebjaerg syndrome.


diaminedichloroplatinum, a heavy metal complex; used as an antineoplastic agent. See also cisplatin.

Patient discussion about DDP

Q. Is pervasive developmental disorder (PDD) or autism is fatal……what exactly it is……?

A. Autism is not fatal in its symptom and progression but it can become fatal as it does impair normal physiological function it CAN BE a fatal condition. It’s a group of illness which involves delays in the development of basic skills. It happens to children below age 3. It affects the child`s ability to communicate and interact. Autism affected children are also found to be mentally retarded.

Q. I was at my colleague's home and one of his kids kept talking to herself he said that she has PDD. i later asked my wife about it and she said she thinks it's a type of autism. but other than talking to herself the girl seemed perfectly normal. so is PDD a light version of autism?

A. I didn't really understand everything in this web page, but I think I get the big picture. Thanx

Q. What resources are available in Seattle, Washington to help with an autistic child?

A. i miss Seattle... here is a link to "Autism Spectrum Treatment and Research (ASTAR) Center". a well know establishment:


More discussions about DDP
References in periodicals archive ?
Whereas in DDP goats daily milk yield and total fat contents were higher in AB and BB genotypes, while all three milk protein fractions were raised in homozygous AA genotype followed by heterozygous AB (Table 3).
EeA[cedilla] Greater Flexibility: DDP |ESS is an extremely flexible solution with support for centrally managed authentication and a broad range of data protection, including hardware- and software-based encryption.
5[micro]g/m1 DDP in curcumin-free medium for 48 h and were harvested with trypsinization at the 90% confluent stage, fixed with cold 70% ethanol, stained by Annexin V-FITC and PI as have described, then assessed for cell apoptosis by flow cytometry (Beckman Coulter, EPICS ALTRA, CA).
In December, the EP system began reporting expired DDPs on the 5th day of the month after the expiration.
No, there is a modified DDP which can be used in cases of alleged 'gross misconduct'.
The final list and recommendations will be presented to the DDP at the July 15th briefing.
DDP is to appeal against the defamation ruling in Hamburg.
com)-- In January 2013, the owner of the website and CEO of Austrian-based Internet Marketing company DDP Marketing Inc.
Certain command areas of Saurashtra, Kutch and North Gujarat besides some parts of Rajasthan fall under DPAP and DDP areas, but are not covered under AIBP, and therefore, the Gujarat Government is not getting requisite benefit under the AIBP scheme.
Talking to Daily Times, an official of COMSTAS said that the DDP provided an alternative path to a foreign degree at highly reduced cost and without physical displacement.