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a platinum coordination compound whose main mode of action resembles that of alkylating agents with production of cross links between the two strands of DNA in the double helix so that DNA cannot be replicated and the cells cannot divide. It is used as an antineoplastic agent in the treatment of metastatic tumors of the testis, ovary, bladder, and head and neck. It can cause serious damage to the kidney, eighth cranial nerve, gastrointestinal tract, and bone marrow, can upset metabolic processes, and can produce hypocalcemia and hypomagnesemia. Called also DDP or cis-DDP.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Notation for the gene for DFN1.
Farlex Partner Medical Dictionary © Farlex 2012

Mohr-Tranebjaerg syndrome

An autosomal recessive neurodegenerative syndrome (OMIM:304700) characterised by postlingual progressive sensorineural deafness as the first presenting symptom in early childhood, followed by progressive dystonia, spasticity, dysphagia, mental deterioration and cortical blindness.

Molecular pathology
Defects of TIMM8A, which encodes a translocase, cause Mohr-Tranebjaerg syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Patient discussion about DDP

Q. Is pervasive developmental disorder (PDD) or autism is fatal……what exactly it is……?

A. Autism is not fatal in its symptom and progression but it can become fatal as it does impair normal physiological function it CAN BE a fatal condition. It’s a group of illness which involves delays in the development of basic skills. It happens to children below age 3. It affects the child`s ability to communicate and interact. Autism affected children are also found to be mentally retarded.

Q. I was at my colleague's home and one of his kids kept talking to herself he said that she has PDD. i later asked my wife about it and she said she thinks it's a type of autism. but other than talking to herself the girl seemed perfectly normal. so is PDD a light version of autism?

A. I didn't really understand everything in this web page, but I think I get the big picture. Thanx

Q. What resources are available in Seattle, Washington to help with an autistic child?

A. i miss Seattle... here is a link to "Autism Spectrum Treatment and Research (ASTAR) Center". a well know establishment:


More discussions about DDP
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References in periodicals archive ?
Samples Collection and Processing of Milk: Two goat breeds, Beetal and DDP, being best dairy animals, were selected for the present study.
The DDP is designed to be a high-performance, online storage system which is simple to connect.
In addition to strong authentication, encryption and threat protection, DDP | ESS addresses security compliance requirements by providing:
For drug combination experiments, cells were cotreated with different concentrations of PL and DDP or TX for 72 hr.
DDP's CEO Alex Giannini stated that his company would use the investment to fund several acquisitions.
You can apply the same DDP settings to the deconvolved image as you did to the original by switching to the unprocessed version and clicking on "Apply to all" in the Display Manager window.
An official with the DDP who asked not to be identified told dpa that the charges were a form of "politics of retribution" being used against Mutharika by Banda.
To investigate the mechanism basis of curcumin as a chemosensitizer in lung cancer, we examined curcumin's effects on HIF-1[alpha] in cis-platin (DDP) sensitive A549 and resistant A549/DDP cell lines by RT-PCR and Western blot.