DCAF7
(redirected from DDB1- and CUL4-associated factor 7)DCAF7
A gene on chromosome 17q23.3 that encodes a protein involved in craniofacial development, which acts upstream of the EDN1 pathway and is required for formation of the upper jaw. DCAF7 associates with DIAPH1 and controls GLI1 transcriptional activity, is involved in skin development, and may be a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.