DTL
(redirected from DDB1- and CUL4-associated factor 2)Also found in: Dictionary, Encyclopedia.
DTL
A gene on chromosome 1q32 that encodes a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, which is required for cell cycle control, DNA damage response and translesion DNA synthesis.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.