DCTN3(redirected from DCTN22)
DCTN3A gene on chromosome 9p13 that encodes dynactin-3 (the smallest subunit of dynactin), a macromolecular complex that binds to both microtubules and cytoplasmic dynein and effect an array of motor activities, including ER-to-Golgi transport, centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning and axonogenesis. Dynactin-3 is primarily an alpha-helical protein; it only exists as a part of the dynactin complex.
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