SAMHD1

(redirected from DCIP)
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SAMHD1

A gene on chromosome 20pter-q12 that encodes a putative nuclease involved in the innate immune response, which acts by downregulating cell-intrinsic antiviral response. It may play a role in mediating pro-inflammatory responses to TNF-alpha signalling. It is expressed in the heart, skeletal muscle, spleen, liver and elsewhere, but not in the brain or thymus.

Molecular pathology
Defects in SAMHD1 cause Aicardi-Goutieres syndrome type 5 and chilblain lupus type 2.
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References in periodicals archive ?
Figure 3 shows that, with different support counts, DCIP consistently uses up a lot less calculation time than Apriori, thus proving that the efficiency of DCIP is superior to that of the traditional Apriori algorithm.
the DCIP (DODD 3020.40) is the DOD plan to protect DIB infrastructure
Recommendation: To help assure the availability of critical infrastructure by improving training and awareness, the Secretary of Defense should direct ASD(HD&ASA) to develop departmentwide DCIP training standards and an implementation time frame to enable the combatant commands and military services to develop consistent and cost-effective training programs.
As a result of those efforts, in early 2006, the Assistant Secretary of Defense for Homeland Defense and America's Security Affairs (ASD (HD&ASA)) issued a comprehensive set of DCIP benchmarks and standards for use with existing IVA protocols.
We measured complex I spectrophotometrically at 600 run in an incubation volume of 1.0 mL containing 25 mmol/L potassium phosphate, 3.5 g/L BSA, 60 [micro]mol/L DCIP, 70 [micro]mol/L decylubiquinone, 1.0 [micro]mol/L antimycine-A, and 0.2 mmol/L NADH, pH 7.8.
Dichlorophenol Indophenol Precipitation (DCIP) test: KKU-DCIP-Clear reagent kit was obtained from KhonKaen University.
NADH-dependent DCIP reduction activities in sonicated mitochondria were reduced by trinexapac-ethyl (Fig.
- The test reagent contained 3.5 mM glucose-6-phosphate, 0.2 mM NADP, 21 [[micro]meter] DCIP, 3.3 [[micro]meter] PMS, and 18.8 mM Mg[Cl.sub.2] in 20 mM Tris-HCl pH 8.0.
It said that based on data provided by the Defense for Children International Palestine (DCIP), among the 57 children killed in 2018 five were in the age group of 0 to 12 years, 29 in the age group of 13 to 15 years, and 23 children were in the age group of 16 to 17 years.
The report notes that of the 56 Palestinian children killed by Israeli forces and settlers in the OPT during 2018, a total of 45 children were killed in the Gaza Strip since March 30, according to evidence collected by DCIP. In the overwhelming majority of cases, DCIP was able to confirm children did not present any imminent, mortal threat or threat of serious injury when killed by Israeli forces.
DCIP (https://www.dci-palestine.org/no_justice_for_50_palestinian_children_killed_in_2018) noted that this year, Israeli forces killed 44 children in Gaza and that the increase in the number of killings coincided with the Great March of Return protests.