DCHS1

DCHS1

A gene on chromosome 11p15.4 that encodes a calcium-dependent cell adhesion protein and putative cadherin; its function is unknown.
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In our study, we found that the over expression of DKK4 might promote the proliferation of tumor cells with unclear mechanism and that there is over expression in genes related to cell adhesion, such as FAT3 , PCDH family (including PCDHAI , PCDHB16 , and PCDH14 ), CDH11 , and DCHS1 , and they participate in the adhesion, migration, differentiation, and signal transmission of cells by adjusting the intercellular interaction and interaction between cell and extracellular matrix; they might also be relevant to the progression of GST.