CLEC12A

(redirected from DCAL-2)

CLEC12A

A gene on chromosome 12p13.2 that encodes a C-type lectin domain receptor which modulates signalling cascades and mediates tyrosine phosphorylation of target MAP kinases.
References in periodicals archive ?
Dendritic cell associated C-type lectin 2 (DCAL-2) alters dendritic cell maduration and cytokine production.
Numerous other groups identified this receptor and named it C-type lectin-like molecule-1 (CLL-1), DC associatedC-type lectin 2 (DCAL-2), and killer cell lectin-like receptor 1 (KLRL1) [153-155].
Dectin-2 (or DCAL-2, Clec6A) or beta-glucan receptor is a C-type lectin receptor expressed on DCs, macrophages, neutrophils, and monocytes (Table 1) [170].
Olson et al., "Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production," Blood, vol.