PKN1

(redirected from DBK)
Also found in: Acronyms, Encyclopedia.

PKN1

A gene on chromosome 19p13.12 that encodes a PKC-related serine/threonine-protein kinase involved in various cellular processes, including regulation of intermediate filaments of the actin cytoskeleton, cell migration, tumour cell invasion and transcription regulation. PKN1 regulates the cytoskeletal network by phosphorylating VIM and neurofilament proteins (e.g., NEFH, NEFL and NEFM), inhibiting their polymerisation; it is a coactivator of androgen receptor.
References in periodicals archive ?
The promotion of DBK Pharma's shares is the first process to be implemented by Pioneers among investors.
In the year to 31 December 2015, DBK had revenues of GBP 12.
DBK is appointed as project manager on the development of the 260,000 sq ft state of the art production facility, which is credited with bringing a new generation of automotive manufacturing back to the Midlands heartlands, as well as acting as quantity surveyor to the project and providing CDMC services.
larinin (14) calismasinda, demir depolari yeterli olan anneler ile yetersiz olan anneler ve bunlarin yenidoganlari arasinda Hb, Htc, MCV, MCH, MCHC, demir, DBK, Tsat ve serum ferritin degerleri acisindan anlamli fark bulunamamistir.
DBK goes the extra mile in finishing off their knives.
DBK is appointed as cost consultant on both Wokingham Industrial Park and Anglo Business Park in Aylesbury.
DBK cookware is sold in open stock and in a 10-piece master set.
It was created for DBK, the German home heater maker, apparently without the firm's knowledge.
According to DBK, the SAG mill cavern will be around the sixth largest underground cavern in the world; 128.
JAMIE SUTTON BUILDING SURVEYOR - DBK PARTNERS LTD JAMIE is currently a Building Surveyor at DBK Partners Ltd where he has been since he became a trainee in 2011.
Ultimately owned by the GOK, DBK plays a strategic role in facilitating the former's goal of diversifying Kazakhstan's economy away from the oil and gas sector.
Development Bank of Kazakhstan and HSBC Bank plc signed a framework agreement to facilitate long term financing with participation of export credit agencies, the press service of the DBK said Wednesay.