DLGAP1

(redirected from DAP1)

DLGAP1

A gene on chromosome 18p11.31 that encodes disks-associated protein 1, which is concentrated in synaptosomal regions of the brain and forms part of the post-synaptic scaffold of neurons.
References in periodicals archive ?
Immunofluorescence results revealed decreased [beta]-catenin immunofluorescence (green) in the cells treated with EGCG; DAP1 counterstaining (blue) was similar in the cells treated with or not treated with EGCG (Fig.
Abbreviations: CPC, chromosomal passenger complex; CYK-4, cytokinesis gene 4; DAP1, 4',6-diamidino-2-phenylindole; DTT, dithiothreitol; GAP, GTPase-activating protein; INCENP, inner centromere protein; MgcRacGAP, male germ cell Rac GTPase-activating protein; MKLP1, mitotic kinesin-like protein I; Rho, Ras homolog family member; RhoA, Ras homolog family member A; RhoGEF Ect2, Rho guanine nucleotide exchange factor epithelial cell transforming sequence 2.
Panel (a) overlay of HBcAg (red) and EpCAM (green) positive cells and DAP1 nuclei counterstaining (blue) in HCC tissue (panels (a1)-(a3), resp.
DAP1 as a fluorescence DNA binding agent was applied to assess nuclear apoptosis.
En ese sentido, dichas respuestas de "rechazo" son excluidas para no subestimar la DAP1.
Immunostained using mouse anti-Src antibody (dilution in 1:100) and Alexa Fluor 488 conjugated goat anti-mouse IgG (1:1000; ThermoFisher Scientific), and counterstained for nuclei with DAP1.
The apoptosis and necrosis induced by total saponins, individual saponins, saponin aglycone and desulfated saponin were detected by DAP1 and PI double staining.
Then, the slides were triple stained with p-VEGFR2 (FLK1/KDR) primary antibody (Cell Signaling, 3817; 1:100), antirabbit IgG conjugated with Alexa Fluor 555 (Cell Signaling, 4413; 1:500) and ProLong Gold antifade reagent with DAP1 (Invitrogen).
Only living cells, identified by DAP1 to stain dead cells were considered for the analyses.
Nuclei were counterstained with DAP1 (4,6-diamidin-2-phenylindol) (1 [micro]/ml) or propidium iodide (1 [micro]/ml).
The slides were afterwards mounted in Prolong Gold anti-fade reagent with DAP1 (invitrogen Molecular Probes), and were inspected with a confocal microscopy (Zeiss 710).