cytotoxicity

(redirected from Cytotoxicity tests, immunologic)
Also found in: Dictionary, Thesaurus.

cytotoxicity

 [si″to-tok-sis´ĭ-te]
1. the degree to which an agent has specific destructive action on certain cells.
2. the possession of such destructive action, particularly in reference to lysis of cells by immune phenomena and to antineoplastic agents that selectively kill dividing cells. adj., adj cytotox´ic.
antibody-dependent cell-mediated cytotoxicity (ADCC) (antibody-dependent cellular cytotoxicity) lysis of target cells coated with antibody by effector cells with cytolytic activity and specific immunoglobulin receptors called Fc receptors, including K cells, macrophages, and granulocytes. Lysis of the target cell is extracellular, requires direct cell-to-cell contact, and does not involve complement.
cell-mediated cytotoxicity destruction of a target cell by specific lymphocytes, such as cytotoxic T lymphocytes or NK cells; it may be antibody-dependent (see antibody-dependent cell-mediated c.) or independent, as in certain cell-mediated hypersensitivity reactions.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cy·to·tox·ic·i·ty

(sī'tō-tok-sis'i-tē),
The quality or state of being cytotoxic.
Farlex Partner Medical Dictionary © Farlex 2012

cy·to·tox·ic·i·ty

(sī'tō-tok-sis'i-tē)
The quality or state of being cytotoxic.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cytotoxicity

The property of being able to cause damage to, or death of, cells.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

cy·to·tox·ic·i·ty

(sī'tō-tok-sis'i-tē)
The qual-ity or state of being cytotoxic.
Medical Dictionary for the Dental Professions © Farlex 2012