* The report reviews key players involved in Cytotoxic T-Lymphocyte
Protein 4 (CTLA-4 or CD152) targeted therapeutics and enlists all their major and minor projects
Bagchi, "Induction of cytotoxic T-lymphocyte
antigen-2[beta], a cysteine protease inhibitor in decidua: a potential regulator of embryo implantation," The Journal of Biological Chemistry, vol.
The in vitro tumor-specific cytotoxic T-lymphocyte
(CTL) response elicited by immunization with mHSP/P was analyzed by means of lactate dehydrogenase release from damaged cells.
Yoshizawa et al., "Association analysis of cytotoxic T-lymphocyte
antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients," Journal of Hepatology, vol.
AMSTERDAM -- The highly promising new class of investigational anticancer agents known at cytotoxic T-lymphocyte
antigen 4 blockers has a characteristic group of side effects, Dr.
Computer-based design of an HLA-haplotype and HIV-clade independent cytotoxic T-lymphocyte
assay for monitoring HIV-specific immunity.
Posttransplant lymphoproliferative disorder results from an expansion of the pool of Epstein-Barr virus (EBV)-infected B cells that are able to evade specific cytotoxic T-lymphocyte
control, secondary to immunosuppressive therapy.
Oral and intranasal insulin appear to be promising approaches, he said, since animal studies suggest that insulin delivered to the mucosa induces insulin antibodies, which in turn reduce cytotoxic T-lymphocyte
Several immunosuppressive effects of EVs have also been reported [21, 32, 33]; for instance, Fas Ligand [(Fas-L).sup.+] EVs released from regulatory T cells are able to inhibit DC-induced cytotoxic T-lymphocyte
(CTL) responses .
The results of a phase Ib/II study of T-VEC and ipilimumab, an anti-CTLA-4 (cytotoxic T-lymphocyte
antigen 4) antibody have been reported.
Recent efforts have focused on the use of recombinant DNA techniques to stimulate cytotoxic T-lymphocyte
While the study remains blinded, cytotoxic T-lymphocyte
responses have been detected 16 of 116 volunteers, suggesting that the prime-boost approach may be appropriate for further clinical study.