cytogenetics (redirected from Cytological band)
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that branch of genetics
devoted to the cellular constituents concerned in heredity, i.e., the chromosomes
clinical cytogenetics the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes.
Cytogenetics arose as a fusion of 19th-century cytology and 20th-century genetics, which came into being in 1903 with the articulation of the chromosome theory of inheritance. The developing field concerned itself with detailing the behavior of chromosomes and their functional subunits, the genes, during reproduction, and with relating that behavior statistically to characteristics of the resulting cells or animals. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been fixed in mitosis and stained with various agents to delineate characteristic bands. DNA probes can be applied to locate specific gene sequences. Karyotyping is the arrangement of photographs of stained chromosomes in a standard format. Cytogenetic techniques are used to test for inborn errors of metabolism and genomic aberrations such as Down syndrome and to determine sex in cases where anatomy is inconclusive.
n. (used with a sing. verb)
The branch of genetics that deals with the cellular components, particularly chromosomes, that are associated with heredity.
cy′to·ge·net′ic, cy′to·ge·net′i·cal adj.
cy′to·ge·net′i·cist (-sĭst) n.
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been arranged as karyotypes. Individuals can be classified according to characteristic banding patterns that appear when the karyotypes are exposed to some dyes. In addition, DNA probes may be applied to locate specific gene sequences. Cytogenetic techniques are used to test for inborn errors of metabolism, for disorders such as Down syndrome, and to determine sex in cases where anatomy is inconclusive.
cytogenetics the study of the inheritance of cells and their chromosomes. Cytogenetic analysis of foetal cells (see AMNIOCENTESIS and CYSTIC FIBROSIS) is used to assess potential risks to the baby.