cytogenetics

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Related to Cytogenetic analysis: cytogeneticist, Cytogenetic map, Chromosome analysis

cytogenetics

 [si″to-jĕ-net´iks]
that branch of genetics devoted to the cellular constituents concerned in heredity, i.e., the chromosomes.
clinical cytogenetics the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks),
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes.

Cytogenetics arose as a fusion of 19th-century cytology and 20th-century genetics, which came into being in 1903 with the articulation of the chromosome theory of inheritance. The developing field concerned itself with detailing the behavior of chromosomes and their functional subunits, the genes, during reproduction, and with relating that behavior statistically to characteristics of the resulting cells or animals. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been fixed in mitosis and stained with various agents to delineate characteristic bands. DNA probes can be applied to locate specific gene sequences. Karyotyping is the arrangement of photographs of stained chromosomes in a standard format. Cytogenetic techniques are used to test for inborn errors of metabolism and genomic aberrations such as Down syndrome and to determine sex in cases where anatomy is inconclusive.

Farlex Partner Medical Dictionary © Farlex 2012

cytogenetics

(sī′tō-jə-nĕt′ĭks)
n. (used with a sing. verb)
The branch of genetics that deals with the cellular components, particularly chromosomes, that are associated with heredity.

cy′to·ge·net′ic, cy′to·ge·net′i·cal adj.
cy′to·ge·net′i·cal·ly adv.
cy′to·ge·net′i·cist (-sĭst) n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks)
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been arranged as karyotypes. Individuals can be classified according to characteristic banding patterns that appear when the karyotypes are exposed to some dyes. In addition, DNA probes may be applied to locate specific gene sequences. Cytogenetic techniques are used to test for inborn errors of metabolism, for disorders such as Down syndrome, and to determine sex in cases where anatomy is inconclusive.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cytogenetics

the study of the inheritance of cells and their chromosomes. Cytogenetic analysis of foetal cells (see AMNIOCENTESIS and CYSTIC FIBROSIS) is used to assess potential risks to the baby.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
For this patient, as well as for other women with Turner syndrome, the necessary routine is cytogenetic analysis (together with genetic counseling).
Cytogenetic analysis in Triatomapseudomaculata Correa and Espinola, 1964 from different Brazilian States (Hemiptera, Triatominae).
In this study, cytogenetic analysis by karyotyping was done for all cases that have clinical features of DS to confirm the clinical diagnosis and to determine the frequency of different types of DS.
Current standards require evaluation by immunohistochemistry (CD-99) and cytogenetic analysis for the diagnosis of ES [14-17].
Array comparative genomic hybridization (aCGH) [2] has improved the analysis and characterization of hematopoietic malignancies (1-4) by both discovering previously unknown copy number (CN) changes [often small cryptic lesions that are not identified by conventional cytogenetic analysis or standard fluorescence in situ hybridization (FISH) testing] and comprehensively characterizing breakpoints of known aberrations (5-6).
A bone marrow biopsy with cytogenetic analysis and fluorescent in situ hybridization (FISH) was performed to evaluate the patient's pancytopenia.
Cytogenetic analysis of fetal tissue after SM is recommended for prognostic and diagnostic purposes, and to give a better estimate of the risk of recurrence in future pregnancies.
Cytogenetic analysis of several pseudomyxoma peritonei lesions originating from mucinous cystadenoma of the appendix.
The diagnosis of rPNET is mainly based on histopathology and immunohistochemistry, supported by cytogenetic analysis. rPNET is characterized by small uniform round cells with focal Homer-Wright rosettes or perivascular seudo-rosettes formation.
Leveraging CPDR's latest discoveries with CytoTest's expertise in cytogenetic analysis and our resources for validating and optimizing genomics-based diagnostic assays, this CRADA is an exciting milestone for CytoTest.”
For cytogenetic analysis, Dyban method, which is a suitable method for analyzing chromosomes of embryo cells, was used with some modifications (34).
All the samples which underwent cytogenetic analysis were processed according to standardized protocols for processing and analysis of peripheral blood samples.