NADH dehydrogenase

(redirected from Cytochrome c reductase)

NADH de·hy·dro·gen·ase

an iron-sulfur-containing flavoprotein reversibly oxidizing NADH to NAD+; an inherited deficiency of this complex results in overwhelming acidosis.
Farlex Partner Medical Dictionary © Farlex 2012

NADH de·hy·dro·gen·ase

(dē-hī'drŏ-jen-ās)
An iron-sulfur-containing flavoprotein reversibly oxidizing NADH to NAD+; an inherited deficiency of this complex results in overwhelming acidosis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
As listed in Table 7, 11 mitochondrial proteins were influenced after diabetic modeling, whereas only four proteins (mitochondrial complex III cytochrome C reductase 2, mitochondrial complex III cytochrome C reductase 1, glutathione peroxidase, and peroxidase) were reversed after TLN treatment in diabetic rats (Table 9).
Precisely, 11 mitochondrial proteins were severely affected after diabetic modeling, including mitochondrial complex III cytochrome C reductase 2, aconitase, mitochondrial complex I NADH-coenzyme Q reductase 5, mitochondrial complex IV cytochrome C oxidase subunit 2, mitochondrial complex III cytochrome C reductase 1, mitochondrial complex II succinate dehydrogenase complex subunit A, mitochondrial complex IV cytochrome C oxidase subunit 1, glutathione peroxidase, uncoupling protein 2, peroxidase, and manganese superoxide dismutase.
Figure 3 shows representative spectrophotometric profiles of absorbance of cytochrome P450 and cytochrome b5 at different wave lengths in different experimental groups, whereas Figure 4 shows the same representative profiles of cytochrome c reductase.
Part of type cytochrome the cbb3-type cytochrome c reductase c oxidase subunit I) cb-type cytochrome C oxidase 0.997 subunit IV, ccoQ Ubiquinol-cytochrome Creductase 0.978 cytochrome B subunit, petB; component of the ubiquinol- cytochrome c reductase Integral membrane protein, Cj1493c 0.965 Ferredoxin domain-containing integral 0.961 membrane protein, Cj0369c Periplasmic protein, Cj1486c 0.950 Ubiquinol-cytochrome Creductase 0.943 iron-sulfur subunit, petA; component of the ubiquinol-cytochrome c reductase Cation-transporting ATPase, Cj1155c 0.932 Cation-transporting ATPase, Cj1161c 0.872
Table 4 shows the effects of asphalt fume inhalation on the microsomal protein content and the NADPH cytochrome c reductase activity of the lung.
Therefore, inhibition of the cytochrome c reductase due to the administration of tadalafil, vardenafil, and sildenafil to the male rats might affect these physiological pathways.
The activities of NADH dehydrogenase (complex I) (18), succinate dehydrogenase (complex II) (19), NADH cytochrome C reductase (complex I and III) (18), succinate cytochrome C reductase (complex II and III) (18), cytochrome C oxidase (complex IV) (20), and citrate synthase (CS) (21) were measured spectrophotometrically using a Beckman DU-650 Spectrophotometer by monitoring the reduction of ferricyanide (complex I), 2,6-dichlorophenolindophenol (complex II), cytochrome C (complex I+III and II+III), the oxidation of cytochrome C (complex W), and the appearance of free coenzyme A (CS) in spermatozoa homogenates as previously described.
Although acetylated cytochrome c has been shown to resist reduction specifically by mitochondrial cytochrome c reductases (Azzi et al., 1975), other reductases released during homogenization may still reduce cytochrome c under the assay conditions.