cytochrome b5 reductase

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cy·to·chrome b5 re·duc·tase

(sī'tō-krōm rē-dŭk'tās),
A flavoenzyme catalyzing the reduction of two molecules of ferricytochrome b5 to two molecules of ferrocytochrome b5 at the expense of NADH; has a role in fatty acid desaturation; a deficiency can lead to hereditary methemoglobinemia (type I, only observed in erythrocyte cytosol; type II, deficiency in all tissues; type III, deficiency in all hematopoetic cells).


any of a class of hemoproteins, widely distributed in animal and plant tissue, whose main function is electron transport; distinguished according to their prosthetic group as a, b, c and d.

cytochrome b5 reductase
a flavoprotein involved in the desaturation of fatty acids in the liver.
cytochrome oxidase
an a type cytochrome which contains copper and receives electrons from another cytochrome, of the c type, and transfers them to oxygen atoms allowing the oxygen to combine with hydrogen atoms to form water. A nutritional deficiency of copper leads to a general reduction in metabolic rate because of the absence of cytochrome oxidase a.
cytochrome system
the sum of cytochromes which play a part in the body's metabolic processes. Includes the cytochrome oxidases and cytochrome reductases.