Surgical excision is demonstrated if the mass persists to adulthood or reaches 5 cm which can lead to risk of developing giant fibroadenoma or cystosarcoma phyllodes
(1, 2, 13).
Phyllodes tumor is a rare biphasic neoplastic lesion of the breast composing of stromal and epithelial components.1 Its incidence is 0.3-1% of all the breast tumors.2 It was first described by the name cystosarcoma phyllodes
by Mullor which was labeled to the present name by WHO classification in 1982.3,4 It is divided into benign and malignant depending upon stromal and atypical cells.5 About 70-90% of tumors are benign.
To the Editor: Phyllodes tumors are rare fibroepithelial malignancies of the breast and account for <1% of all malignant breast tumors. It is difficult to distinguish from fibroadenomas, while malignant cystosarcoma phyllodes
can grow in size quickly and metastasize early. Gigantic cystosarcoma phyllodes
of the breast is very rare, thus limiting our understanding of the disease and influencing diagnostic and management outcomes.
Stromal sarcomas of the breast: a unified approach to connective tissue sarcomas other than cystosarcoma phyllodes
Primary osteosarcoma of the breast is a rare and aggressive malignancy that should be differentiated from two other similar tumors: metaplastic carcinoma and cystosarcoma phyllodes
. Due to the rarity and poor prognosis of this disease, it is important that radiologists recognize its mammographic features in order to ensure proper management and optimize patient outcomes.
But 1 case was misdiagnosed as malignancy and turned out to be benign cystosarcoma phyllodes
, a benign lesion.
Klein, "Cystosarcoma phyllodes
arising synchronously in right breast and bilateral axillary ectopic breast tissue," Archives of Pathology and Laboratory Medicine, vol.
Cosgrove, "Osteogenic sarcoma of the breast arising in a cystosarcoma phyllodes
: a case report and review of the literature," Journal of Medical Case Reports, vol.
Jones, "Immunohistochemical profile of cystosarcoma phyllodes
of the breast: a study of 23 cases," Breast Journal, vol.
El termino original de Cystosarcoma Phyllodes
fue acunado por Johannes Muller en 1838 para denominar un tumor que macroscopicamente tenia la apariencia de la carne de pescado (2).
Virginal hypertrophy, giant fibroadenoma, and cystosarcoma phyllodes
are the important differential diagnoses to be considered when one encounters a large breast mass.
, also called phyllodes tumor, can likewise cause a rapidly growing large mass in adolescents that also warrants removal.