cyclooxygenase

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Related to Cycloxygenase: Cyclooxygenase 2 inhibitors

cyclooxygenase

 [si″klo-ok´sĭ-jĕ-nās]
an activity of the enzyme prostaglandin endoperoxide synthase.

pros·ta·glan·din en·do·per·ox·ide syn·thase

a protein complex that catalyzes two steps in prostaglandin biosynthesis; the cyclooxygenase activity (which is inhibited by aspirin and indomethacin) converts arachidonate and 2O2 to prostaglandin G2; the hydroperoxidase activity uses glutathione to convert prostaglandin G2 to prostaglandin H2.
Synonym(s): cyclooxygenase

cyclooxygenase

/cy·clo·oxy·gen·ase/ (-ok´sĭ-jen-ās) a component of prostaglandin synthase (q.v.).

cyclooxygenase

(sī′klō-ŏk′sĭ-jə-nās′, -nāz′)
n.
1. See COX-1.
2. See COX-2.

cyclooxygenase

[si′klō·ok′səjĕnās]
an activity of the enzyme prostaglandin endoperoxide synthase.

Cyclooxygenase

An enzyme, found in most tissues, that helps turn some fatty acids into protaglandins.
Mentioned in: Cox-2 Inhibitors
References in periodicals archive ?
Suppressive effect of natural sesquiterpenoids on inducible cycloxygenase (COX-2) and nitric oxide synthase (iNOS) activity in mouse macrophase cells.
Natural products like esculetin, fraxetin, daphnetin and other related coumarin derivatives are recognized as inhibitors of the lipoxygenase and cycloxygenase enzymic systems, and of neutrophil-dependent superoxide anion generation (Fylaktakidou et al.
The abdominal writhing induced by acetic acid involves the production and release of arachidonic acid metabolites via cycloxygenase (COX) and prostaglandin biosynthesis (Elisabetsky et al.
Moreover, activities on 12-lipoxygenase from human platelets and cycloxygenase (COX)-1 and -2 from sheep cotyledons and seminal vesicles, respectively, have been evaluated.