anaphase promoting complex

(redirected from Cyclosome)

anaphase promoting complex

A large protein complex of 11 to 13 proteins—including cullin (Apc2), RING (Apc11), and other proteins of as yet unknown functions—which is an E3 ubiquitin ligase that targets cell cycle proteins for degradation by the 26S proteasome.
References in periodicals archive ?
Yongyi Hi-Tech Nutraceuticals will feature Hi-Tech's proprietary Cyclosome technology and its high absorption ingredients at several upcoming US trade shows.
Objective: This research proposal describes an ambitious effort to characterize structurally and biochemically ubiquitin chain initiation and elongation by the anaphase-promoting complex or cyclosome (APC/C) in complex with two well-characterized substrates.
In oridonin-treated HepG2 cells, the up-regulation of Stil might inhibit the formation of 20S cyclosome complex (Yamashita et al.
Additionally, having access to our extensive production capabilities across a variety of product formats such as Liposomal Technology, Cyclosome Technology that combines cyclodextrin and liposomal delivery systems; and Time-Released Monolithic Osmotic Pump (TMOP) delivery systems.