danazol

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danazol

 [dan´ah-zol]
a synthetic androgen that suppresses the ovarian-pituitary axis by inhibiting the release of gonadotropins from the pituitary gland; administered orally for treatment of endometriosis, fibrocystic disease of the breast, hereditary angioedema, and gynecomastia.

da·na·zol

(dā'nă-zol),
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema. Indirectly reduces estrogen production by lowering levels of follicle-stimulating hormone and luteinizing hormone.

danazol

/dan·a·zol/ (dah´nah-zōl) an anterior pituitary suppressant used in the treatment of endometriosis, fibrocystic breast disease, and gynecomastia and the prophylaxis of attacks of hereditary angioedema.

danazol

[dan′əzol]
a synthetic androgen that acts to suppress the output of gonadotropins from the pituitary, suppress ovarian hormone production, and directly block ovarian hormone receptors.
indications It is prescribed in the treatment of endometriosis, fibrocystic breast disease, and hereditary angioedema when alternative hormonal therapy is ineffective, contraindicated, or intolerable.
contraindications Genital bleeding; cardiac, liver, or kidney dysfunction; or known hypersensitivity to this drug prohibits its use. It is not prescribed during pregnancy or lactation.
adverse effects Among the most serious adverse reactions are muscle spasms, nausea, weight gain, acne, edema, oily skin, voice changes, and other androgenic effects.

danazol

Endocrinology A non-virilizing anabolic androgen used to manage HANE, fibrocystic breast disease, endometriosis, and possibly autoimmune hemolytic anemia and autoimmune thrombocytopenia, but may mediate immune thrombocytopenia Adverse effects Weight gain, edema, acne, hirsutism, deepening of voice, clitorimegaly, menometrorrhagia, ↓ HDL-C, ↑ liver enzymes, peliosis hepatis, benign intracranial HTN. See Hereditary angioneurotic edema.

da·na·zol

(dā'nă-zol)
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema. Indirectly reduces estrogen production by lowering levels of follicle-stimulating hormone and luteinizing hormone.

da·na·zol

(dā'nă-zol)
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema.

danazol

(dan´əzol´),
n brand name: Danocrine;
drug class: androgen, α-ethinyl testosterone derivative;
action: decreases FSH and LH output;
uses: endometriosis, prevention of hereditary angioedema, fibrocystic breast disease.

danazol

an attenuated androgen that suppresses the ovarian-pituitary axis by inhibiting the release of gonadotropins from the pituitary gland. In animals, it has been used in the treatment of immune-mediated disorders, including anemia and thrombocytopenia.