cyclic nucleotide

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Related to Cyclic nucleotides: cyclic nucleotide phosphodiesterase

cy·clic nu·cle·o·tide

a nucleoside monophosphate in which the phosphoryl group is linked twice to the sugar moiety; for example, adenosine 3',5'-cyclic monophosphate (cAMP).


pertaining to or occurring in a cycle or cycles. The term is applied to chemical compounds that contain a ring of atoms in the nucleus.

cyclic adenosine monophosphate (AMP)
see cyclic adenosine monophosphate.
cyclic guanosine monophosphate (cGMP)
see cyclic guanosine monophosphate.
canine cyclic hematopoiesis
an abnormality of hematopoietic stem cells that results in detectable, cyclic fluctuations in numbers of circulating neutrophils. Affected dogs have an increased susceptibility to infections. The condition is inherited as an autosomal recessive in collies where it is occurs with a distinctive silver-gray coat color; called also gray collie syndrome.
cyclic neutropenia
see canine cyclic hematopoiesis (above).
cyclic non-breeder cows
cows demonstrating estrus regularly but not being submitted for mating; deferral of mating.
cyclic nucleotide
see cyclic nucleotide.
References in periodicals archive ?
Vascular cyclic nucleotide phosphodiesterases (PDE1, PDE3, PDE4 and PDE5) were purified from smooth muscle of bovine aorta (Lugnier et al.
BFBO inhibits the activity of vascular cyclic nucleotide phosphodiesterase isoforms
Thus, two opposing cyclic nucleotide pathways may simultaneously regulate the activity of the respective molecular motors responsible for aggregation and dispersion in a tug-of-war manner--increased cGMP and [Ca.
In previous investigations we used 8-bromo analogs of cyclic nucleotides, which because of their hydrophilicity are poorly permeable through cell membranes (11).
This study showed that decreased antiaggregatory action of the cyclic nucleotides cAMP and cGMP in platelets of individuals with central obesity was associated with decreased phosphorylation of VASP at specific sites, reflecting impaired activation of PKA and PKG.
Effects of phosphodiesterase inhibitors and cyclic nucleotides on sperm respiration and motility.
The stimulation of bovine epididymal sperm metabolism by cyclic nucleotide phosphodiesterase inhibitors.
The dye is made up of these cyclic nucleotides and so acts as fuel for the cells.
Editor's Note: Cyclic AMP and GMP are cyclic nucleotides related to adenine and guanine, two major building blocks in DNA and RNA.
Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.
Forskolin interaction with voltage-dependent K channels in Helix is not mediated by cyclic nucleotides.