Beavo, "Identification of inhibitory and calmodulin-binding domains of the PDE1A1 and PDE1A2 calmodulin-stimulated cyclic nucleotide
phosphodiesterases, " The Journal of Biological Chemistry, vol.
Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide
Vandecasteele, "Compartmentation of Cyclic Nucleotide
Signaling in the Heart The Role of Cyclic Nucleotide
Fidock, "Cloning and characterization of the human and mouse PDE7B, a novel cAMP-Specific cyclic nucleotide
phosphodiesterase," Biochemical and Biophysical Research Communications, vol.
Effects of phosphodiesterase inhibitors on tension induced by norepinephrine and accumulation of cyclic nucleotides
in iso- lated human prostatic tissue.
of Glasgow, UK) present the first major compendium on the science of cyclic nucleotide
phosphodiesterases (PDEs) and their therapeutic and biomedical applications in some 15 years, a period during which new mammalian PDE families have been discovered and characterized and PDE-selective inhibitors have been successively marketed (including Viagra, Levitra, and Cialis).
The reduced platelet antiaggregatory activity exerted by both cyclic nucleotides
(11) does not necessarily lead to impaired activation of cyclic nucleotide
/specific kinase/ VASP pathways.
The stimulation of bovine epididymal sperm metabolism by cyclic nucleotide
Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide
The award recognized the professors' contribution in the "demonstration that stimulation of the cyclic nucleotide
signaling pathways can affect guidance molecules, the growth cone, and inhibition of axon regeneration in the injured spinal cord."
Leavesley, "Perspectives on: Cyclic nucleotide
microdomains and signaling specificity: Can we decipher the information content contained within cyclic nucleotide