CYCS

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CYCS

A gene on chromosome 7p15.3 that encodes cytochrome c, an electron carrier protein, which transfers electrons from the heme group of the cytochrome c1 subunit of cytochrome reductase to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. CYCS plays a role in apoptosis by suppressing anti-apoptotic members or by activating pro-apoptotic members of the Bcl-2 family, leading to altered mitochondrial membrane permeability and the release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 activates caspase-9, which then accelerates apoptosis by activating other caspases.

Molecular pathology
Defects in CYCS cause thrombocytopaenia type 4.
References in periodicals archive ?
In CYC, Time is a physical quantity possessed by TemporalObjects (such as Events).
The CYC committee was privileged to locate some amazing donated talent for the event.
CyC publicaba tambien recorridos, visitas y descripciones de las fabricas que publicitaban en sus paginas, lo que operaba igualmente como publicidad.
Other therapies that have been used include high-dose CS, CYC, IVIGs and rituximab.
Seacraft continued to highlight the activities of the CYC and the Sydney Hobart Race, the Christmas 1947 edition carried an extensive preview of the third annual Sydney Hobart Race.
CYC also reports gradually increasing patient numbers at the Macquarie University Hospital.
SPORTING DAYS: Syd Nobel, below and back, third right, with Birkby CYC under 18s.
The PL supplement was virtually indistinguishable from the CYC supplement in taste, color, and consistency.
ANOTHE no family behaviou A smal own - and the hono Perh cyc a nI A small achievement, but my own - and still no recognition in the honours list.
A natural Mahonian partner for cyc was found by Petersen [7].
Price would like to thank the support of his sponsors at CYC Logistics and Tommy at Southwark Metals.