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an analogue of cyanocobalamin (vitamin B12) having exceptionally long-acting hematopoietic activity; used in the treatment of pernicious anemia and other macrocytic anemias.


Vitamin B12b, differing from cyanocobalamin (vitamin B12) in the presence of a hydroxyl ion in place of the cyanide ion at the sixth coordinate position on the cobalt atom.
See also: vitamin B12.
Synonym(s): hydroxocobemine


/hy·droxo·co·bal·a·min/ (hi-drok″so-ko-bal´ah-min) a hydroxyl-substituted cobalamin derivative, the naturally occurring form of vitamin B12 and sometimes used as a source of that vitamin.


A chemical compound, also called vitamin B12a, which is the immediate precursor to cyanocobalamin (vitamin B12) in the body and that has also been investigated as an antidote in cyanide poisoning, although it is not currently approved for such use in the U.S.
See also: amyl nitrite, sodium nitrite, sodium thiosulfate
Synonym(s): hydroxocobalamin.


Vitamin B12. This is the specific treatment for PERNICIOUS ANAEMIA and is highly effective unless neurological damage has already occurred. The drug is on the WHO official list. Brand names are Cobalin-H and Neo-Cytamen.

hydroxocobalamin, hydroxycobalamin

an analog of cyanocobalamin (vitamin B12) having exceptionally long-acting hematopoietic activity. Called also vitamin B12b.
References in periodicals archive ?
King's College Hospital confirmed that three of its 12 Grenfell patients were treated with the hydrogen cyanide antidote Cyanokit.
The purchase of the following medicines: Novastan, Defitelio, Xiapex, Cyanokit and Thyrogen from Swedish Orphan Biovitrum AS and Sanofi Aventis Norge, respectively.
M2 PHARMA-April 29, 2011-Merck Serono gets FDA nod for new presentation of Cyanokit 5 g(C)2011 M2 COMMUNICATIONS
29 April 2011 - Switzerland-based Merck Serono, a division of Merck KGaA, announced today that a new presentation of Cyanokit 5 g (hydroxocobalamin) has been approved by the US Food and Drug Administration (FDA).
In USA, Cyanokit is currently available in a kit comprising two 2.
Cyanokit is indicated for the treatment of known or suspected cyanide poisoning.
NORDIC BUSINESS REPORT-1 April 2010-Swedish Orphan Biovitrum to expand Cyanokit distribution(C)1994-2010 M2 COMMUNICATIONS http://www.
1 April 2010- Biotech company Swedish Orphan Biovitrum (STO: BVT) said today it agreed with Merck Serono, a unit of German pharma company Merck KGaA (ETR: MRK), to expand the distribution of the antidote Cyanokit to Ireland, the UK and the Netherlands.
The Swedish company currently distributes Cyanokit, or hydroxocobalamin, in the Nordic and the Baltic countries.
M2 EQUITYBITES-1 April 2010-Swedish Orphan Biovitrum to expand Cyanokit distribution(C)2010 M2 COMMUNICATIONS http://www.
Acquisition and delivery kits Cyanokit 5 G powder for solution for infusion.
CYANOKIT Antidote is a registered trademark of Merck Sante S.