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an analogue of cyanocobalamin (vitamin B12) having exceptionally long-acting hematopoietic activity; used in the treatment of pernicious anemia and other macrocytic anemias.


Vitamin B12b, differing from cyanocobalamin (vitamin B12) in the presence of a hydroxyl ion in place of the cyanide ion at the sixth coordinate position on the cobalt atom.
See also: vitamin B12.
Synonym(s): hydroxocobemine


/hy·droxo·co·bal·a·min/ (hi-drok″so-ko-bal´ah-min) a hydroxyl-substituted cobalamin derivative, the naturally occurring form of vitamin B12 and sometimes used as a source of that vitamin.


A chemical compound, also called vitamin B12a, which is the immediate precursor to cyanocobalamin (vitamin B12) in the body and that has also been investigated as an antidote in cyanide poisoning, although it is not currently approved for such use in the U.S.
See also: amyl nitrite, sodium nitrite, sodium thiosulfate
Synonym(s): hydroxocobalamin.


Vitamin B12. This is the specific treatment for PERNICIOUS ANAEMIA and is highly effective unless neurological damage has already occurred. The drug is on the WHO official list. Brand names are Cobalin-H and Neo-Cytamen.

hydroxocobalamin, hydroxycobalamin

an analog of cyanocobalamin (vitamin B12) having exceptionally long-acting hematopoietic activity. Called also vitamin B12b.
References in periodicals archive ?
CYANOKIT Antidote is a registered trademark of Merck Sante S.
As the only FDA-approved treatment that can be given to victims of suspected cyanide poisoning, Cyanokit provides emergency first-responders with a critical care medication to treat patients immediately at the scene of a fire or other accident as well as in a hospital emergency room.
Because cyanide poisoning acts very quickly, the immediate quick response capability that Cyanokit provides at the scene of an emergency will be critical in treating known or suspected victims of cyanide poisoning.
Florida's stocking of Cyanokit in its EMS and fire vehicles reflects a recognition by State officials that first responders need to be prepared to treat cyanide poisoning immediately in an emergency," said Carolyn Myers, Ph.
Cyanokit is indicated for the treatment of known or suspected cyanide poisoning.
Prior to administration of Cyanokit, smoke-inhalation victims should be assessed for: exposure to fire or smoke in an enclosed area; presence of soot around the mouth, nose or oropharynx; altered mental status.
If the decision is made to administer another antidote with Cyanokit, these drugs should not be administered in the same IV line.
This year's winners are: -- Bound Tree Medical CYANOKIT -- Dreamwest Innovations SwiftGrip Rapid Intubation System -- Ferno LBS, Jr.
By simplifying the reconstitution and administration processes, we believe that the new Cyanokit 5 g presentation represents a major improvement, allowing for rapid management of cyanide poisoning, a vital asset particularly when treating more than one victim.
First responders will also learn about the Cyanokit or Hydroxocobalamin, an effective and safe antidote for acute cyanide poisoning from fire smoke.
Acquisition and delivery kits Cyanokit 5 G powder for solution for infusion.