cutaneous T cell lymphoma

(redirected from Cutaneous T-cell lymphomas)

cutaneous T cell lymphoma

Mycosis fungoides Oncology A heterogeneous group of relatively uncommon NHLs, which first appear on the skin Epidemiology ±1000 cases occur/yr, US, affecting ages 50-60; ♂:♀ ratio, 2:1; black:white, 2:1 Clinical Long–4-10 yrs Hx of eczematous rashes, which may evolve to parapsoriasis en plaque or poikiloderma atrophicans vasculare  Pathology Epidermotropism, paracortical proliferation in lymph nodes, periarterial proliferation in spleen; aggregates of epithelioid cells, prominent vascular channels, BM involvement Management Nitrogen mustard, BCNU, PUVA therapy, RT Response rate 80% if T1; 30–60% if T2; 20% if T3. See Redman syndrome, Sézary syndrome.
References in periodicals archive ?
cutaneous T-cell lymphomas and identified 5 cases of primary cutaneous acral [CD8.
Primary cutaneous T-Cell lymphomas showing gamma-delta ([gamma][delta]) phenotype and predominantly epidermotropic pattern are clinicopathologically distinct from classic primary cutaneous [gamma][delta] T-Cell lymphomas.
Caption: Cutaneous T-cell lymphomas are non-Hodgkin lymphomas.
Topical resiquimod was effective and well tolerated in patients with early-stage cutaneous T-cell lymphoma (CTCL), in some cases inducing regression in both treated and untreated lesions, according to researchers.
Primary cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of lymphomas that maybe present in the skin without any evidence of extracutaneous disease at the time of diagnosis [1, 2].
Recombinant human interleukin-12 induces lesion regression in some cutaneous T-cell lymphomas, reported Dr.
Common skin cancers include basal cell and squamous cell carcinomas, Kaposi's sarcomas, adnexal tumors, and cutaneous T-cell lymphomas.
Based on these results, Allos intends to continue investigating the role of FOLOTYN as an option for patients with cutaneous T-cell lymphomas.
T-cell lymphoproliferative disorders (26,27) are among the commonest cutaneous T-cell lymphomas (second to MF), accounting for about 30% of all cases and encompassing 3 diseases: lymphomatoid papulosis (LyP), cutaneous anaplastic large cell lymphoma (C-ALCL), and borderline cases.
Cutaneous T-cell lymphomas, or CTCLs, are comprised of a number of indolent non-Hodgkin's T-cell lymphomas, including mycosis fungoides and Sezary syndrome, which have their primary manifestations in the skin.
small/medium T-cell lymphoma (PC-SMTCL) began in the early 1990s when the updated Kiel classification system (1,2) was applied to primary cutaneous T-cell lymphomas that did not meet criteria for mycosis fungoides (MF) or Sezary syndrome.
Cutaneous T-cell lymphomas, or CTCLs, are comprised of a number of non-Hodgkin's T-cell lymphomas, including mycosis fungoides and Sezary syndrome, which have their primary manifestations in the skin.