SOD1

(redirected from Cu,Zn superoxide dismutase)

SOD1

A gene on chromosome 21q22.11 that encodes a soluble, copper- and zinc-binding cytoplasmic protein, which is responsible for destroying free superoxide radicals in the body, converting natural—but harmful—superoxide radicals to molecular oxygen and hydrogen peroxide.

Molecular pathology
SOD1 mutations have been linked to familial amyotrophic lateral sclerosis.
References in periodicals archive ?
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation," Science, vol.
Identification and subcellular localization of a novel Cu,Zn superoxide dismutase of Mycobacterium tuberculosis.
Isolation of an active and heat-stable monomeric form of Cu,Zn superoxide dismutase from the periplasmic space of Escherichia coli.