enoyl-CoA hydratase

(redirected from Crotonase)

en·o·yl-CoA hy·dra·tase

(ēn'ō-il hī'dră-tās),
Δ2-eoyl-CoA hydratase; an enzyme catalyzing a reversible reaction between an l-3-hydroxyacyl-CoA and a 2,3- (or 3,4-) trans-enoyl-CoA in fatty acid degradation.
Synonym(s): crotonase, enoyl hydrase
References in periodicals archive ?
During the conversion of acetyl-CoA into butyryl-CoA thiolase crotonase 3-hydroxybutyryl-CoA dehydrogenase and butyryl-CoA dehydrogenase are played vital roles as key enzymes.
This could only occur when C2=C3 in 2-hexenoyl-CoA is hydrated to L-3-hydroxyhexanoyl CoA by 2-enoyl-CoA hydratase (crotonase; EC 4.2.1.17).
The enzymes located within the mitochondrial matrix are responsible for [beta]-oxidation ofthe medium- to shortchain acyl-CoA intermediates, including long-chain, medium-chain, and short-chain acyl-CoA dehydrogenases; a short-chain hydratase, also named crotonase; a medium-/short-chain 3-hydroxyacyl-CoA-dehydrogenase; and both medium-chain and short-chain 3-keto acyl CoA thiolases (17).