a procedure vital in blood transfusions and organ transplantation. The recipient's erythrocytes or leukocytes are incubated with the donor's serum and vice versa. Various testing procedures are then performed to ensure that the donor and recipient have blood group compatibility or histocompatibility. Also written cross matching and cross-matching.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
1. The process of mixing a sample of the donor's red blood cells with the recipient's serum (major crossmatching) and mixing a sample of the recipient's blood with the donor's serum (minor crossmatching). It is done before transfusion to determine compatibility of blood.
2. The determination of the compatibility of a donated organ's human leukocyte antigens with the recipient's antigens.illustration
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