cross-matching

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cross-match·ing

(kros'match'ing),
1. A test for incompatibility between donor and recipient blood, carried out before a transfusion to avoid potentially lethal hemolytic reactions between the donor's red blood cells and antibodies in the recipient's plasma, or the reverse; performed by mixing a sample of red blood cells of the donor with plasma of the recipient (major crossmatch) and the red blood cells of the recipient with the plasma of the donor (minor crossmatch). Incompatibility is indicated by clumping of red blood cells and contraindicates use of the donor's blood.
2. In allotransplantation of solid organs (for example, kidney), a test for identification of antibody in the serum of potential allograft recipients that reacts directly with the lymphocytes or other cells of a potential allograft donor; presence of these antibodies usually, if not always, contraindicates the performance of the transplantation because virtually all such grafts are subject to a hyperacute type of rejection.

cross-match·ing

(kraws'mach-ing)
1. A test for incompatibility between donor and recipient blood, carried out before transfusion to avoid hemolytic reactions between the donor's red blood cells and antibodies in the recipient's plasma, or the reverse; performed by mixing a sample of red blood cells of the donor with plasma of the recipient (major cross-match) and the red blood cells of the recipient with the plasma of the donor (minor cross-match). Incompatibility is indicated by clumping of red blood cells and contraindicates use of the donor's blood.
2. In allotransplantation of solid organs (e.g., kidney), a test for identification of antibody in the serum of potential allograft recipients that reacts directly with the lymphocytes or other cells of a potential allograft donor; presence of these antibodies usually, if not always, contraindicates the performance of the transplantation because virtually all such grafts will be subject to a hyperacute type of rejection.

cross-matching

A test of the compatibility of blood intended to be transfused. Serum from the donor's blood is mixed with red cells from the recipient's blood. If the bloods are incompatible, the red cells will clump together (agglutination). See also BLOOD TRANSFUSION.
References in periodicals archive ?
Data was collected using a pre-tested questionnaire on age, gender, department, haemoglobin levels, indications of blood transfusions, types of product advised, total number of units ordered, cross-matched and transfused.
Basically, if you want to get your predictability for a good cross-match, very high, you need to try to list every possible antibody that can be detected by the most sensitive techniques.
Sadly, no cross-match was found for the Nuneaton dad because of his rare tissue type - but at least eight leukaemia victims around Britain were matched.
"Graduate Wales is significantly ahead of equivalent facilities elsewhere in the UK, both in terms of its sheer capacity and the level of detail it can process and cross-match, " Mr Carter said.
They said they will cross-match DNA from the clothing of the hitchhiker's body - which was found 40 miles south of Alice Springs - with DNA collected during the investigation of the disappearance of tourist Peter Falconio.
In the unlikely event that a patient without risk factors needed an urgent blood transfusion, she could be given O-negative blood while a type and cross-match is performed.
Every blood bank had the big cross-match rack for microscopic reading of cross-match tubes; it took years for me to find another of those "railroad track" racks.
They hoped to become a life-saving cross-match for Graham and others like him.
Q For years, the benchmark for a quality-assurance (QA) marker in the blood bank has been monitoring the cross-match to transfusion ratio.
Since 50-year-old Graham was diagnosed with lymphoma, more than 1,000 Nuneaton people have given a blood sample, hoping to become a cross-match for Graham and others like him.
He is a rare tissue type - but Nuneaton Borough Supporters Club set up a mobile unit in the town's Market Place in the hope of finding a suitable cross-match for him.