Nature of colonic changes Number of cases (%) Colitis 15 (68.1) (i) Type (a) Chronic quiescent 3 (b) Chronic active 4 (c) Acute/active 5 (ii) Severity (a) Mild 5 (b) Moderate 5 (c) Severe 2 (iii) Extent (a) Focal 3 (b) Diffuse 1 (iv) Others 3 (a) Stricture 1 (b) Granulomatous inflammation 1 (c) Eosinophilic colitis 1 Colonic polyps 5 (22.7) (i) Juvenile polyp/hamartomatous polyp (
Cronkhite-Canada syndrome) 2 (ii) Conventional polyp (tubular adenoma, 2 FAP+) (iii) Hyperplastic polyp 1 Mucosal prolapse/solitary rectal ulcer 2 (9.0) Total number of cases 22
Goto, "Cronkhite-Canada syndrome: epidemiological study of 110 cases reported in japan," Nihon Geka Hokan, vol.
Wolfsen, "Pharmacological management of Cronkhite-Canada syndrome," Expert Opinion on Pharmacotherapy, vol.
Montgomery, "Cronkhite-Canada syndrome six decades on: the many faces of an enigmatic disease," Journal of Clinical Pathology, vol.
Osborn et al., "Clinicopathologic features and treatment outcomes in Cronkhite-Canada syndrome: support for autoimmunity," Digestive Diseases and Sciences, vol.
This also highlights the importance of considering Cronkhite-Canada syndrome as a rare possibility in a middle aged male presenting with haematochezia, specially if the patient is of Asian origin and if there are any cutaneous abnormalities suggestive of this condition.
Surgical treatment of Cronkhite-Canada syndrome associated with protein-losing enteropathy: report of a case.
A case of Cronkhite-Canada syndrome and a review of gastrointestinal polyposis syndromes.
Corticosteroid-responsive Cronkhite-Canada syndrome complicated by thrombosis.
Tsukamoto et al., "Cronkhite-Canada syndrome with colon cancer, portal thrombosis, high titer of antinuclear antibodies, and membranous glomerulonephritis," Journal of Gastroenterology, vol.
Gupta, "Cronkhite-Canada syndrome: a report of two familial cases," Indian Journal of Gastroenterology, vol.
Ng, "Medical management of Cronkhite-Canada syndrome," Southern Medical Journal, vol.
