creatine

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creatine

 [kre´ah-tin]
a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for muscle contraction.
creatine kinase an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.

cre·a·tine

(krē'ă-tēn, -tin), Do not confue this word with creatinine.
A compound, N-(aminoiminomethyl)-N-methylglycine, which occurs in urine, sometimes simply as creatine, but generally as creatinine, and in muscle, generally as phosphocreatine. Elevated levels are found in the urine of individuals with muscular dystrophy.

creatine

(krē′ə-tēn′, -tĭn) also

creatin

(-tĭn)
n.
A compound, C4H9N3O2, that is found in the muscle tissue of vertebrates mainly in the form of phosphocreatine and that is involved in storing and supplying energy for muscle contraction.

cre·a·tine

(krē'ă-tin)
N-(aminoiminomethyl) - N-methylglycine; occurs in urine, sometimes as such, but generally as creatinine, and in muscle, generally as phosphocreatine; elevated in urine in muscular dystrophy; synthesized in liver and pancreas from amino acids; absorbed in bloodstream, it is deposited in tissue (e.g., muscles, brain).

creatine

A nitrogenous substance present in all muscle cells.

creatine

a white nitrogenous substance found in vertebrate muscles.

Patient discussion about creatine

Q. Q. I want to know about urine protein creatine ratio in diagnosing nephrotic syndrome. Please explain interms of unit such as mg/mg or mmol/mg. Normal range, nephrotic range with good referrence.

A. Nephrotic syndrome is defines as a damage to the kidneys, in which there is a leak of large amounts of protein (over 3.5 grams of protein / 24 hours urine output) from the blood to the urine. Protein loss causes low protein count in the blood (hypoalbuminemia) and edemas (excess fluid in the interstitial cavity which is between the cells, causes leg swelling most often, and also in the adbomen and around the eyes).

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