cosmid

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cos·mid

(koz'mid),
A recombinantly engineered plasmid, a circular DNA containing, in order: a plasmid origin of replication and a drug-resistance marker, the cos (cohesive end) site from bacteriophage λ, and a fragment of eukaryotic DNA to be cloned; cosmids are constructed to permit cloning of fragments of up to about 40,000 base pairs in length, with one or more unique restriction sites being necessary to facilitate cloning.

cosmid

(kŏz′mĭd)
n. Genetics
An artificially constructed plasmid used for cloning large genes or other DNA sequences.

cosmid

a class of CLONING VECTOR which comprises a bacterial PLASMID and the COS SITE of a BACTERIOPHAGE, typically bacteriophage lambda. A cosmid combines features of plasmids and of bacteriophages and can be used in CLONING. Large DNA fragments, up to 40 KILOBASE pairs in size, can be cloned in cosmids. The cosmid can be propagated as a plasmid in vivo and packaged into bacteriophages in vitro.

cosmid

a class of plasmid-based vectors carrying the bacteriophage λ cos sequences required for packaging of DNA into phage particles. Used for cloning large DNA fragments (up to 45 kilobases). Recombinant molecules constructed using cosmids are incorporated into bacteriophage using in vitro packaging extracts and introduced with high efficiency into Escherichia coli.
References in periodicals archive ?
Para demostrar lo anterior, Sperber (2002) propone como instancias necesarias, la construccion de la historia filogenetica de los modulos (Tooby & Cosmides, 1992); las conexiones entre analizadores de entrada y controladores motores; y la existencia de un dispositivo inferencial que no se encuentre ligado a receptores sensoriales.
161) For a discussion of evolutionary psychology, see Leda Cosmides & John Tooby, Cognitive Adaptations for Social Exchange, in The Adapted Mind, supra note 149, at 163-225; Leda Cosmides & John Tooby, Neurocognitive Adaptations Designed for Social Exchange, in The Handbook of Evolutionary Psychology, supra note 89, at 584-623.
33) Leda Cosmides and John Tooby, 'Better than Rational: Evolutionary Psychology and the Invisible Hand' (1994) 84(2) American Economic Association Papers and Proceedings 327.
Cosmides is an evolutionary psychologist; Tooby an anthropologist.
See John Tooby and Leda Cosmides, "The Psychological Foundations of Culture," in The Adapted Mind: Evolutionary Psychology and the Generation of Culture, eds.
Para discutir os modelos explicativos para o fenomeno e sua ontogenese e importante a perspectiva da Psicologia Evolucionista (PE), abordagem que propoe estudar a mente humana como resultante de processos adaptativos originados por selecao natural em nosso Ambiente Ancestral de Evolucao (AAE; Barkow, Cosmides, & Tooby, 1992).
por ejemplo, Lumsden y Wilson 1981, Tooby y Cosmides 1992, Richerson y Boyd 2005); por otro lado se ubican los enfoques por analogia, que consideran que cualquier proceso que muestre caracteristicas selectivas compatibles con el modelo darwinista puede analizarse independientemente del sustrato biologico (Dawkins 1976, Dennett 1995).
Research from the psychologist Gerd Gigerenzer, supported by further evolutionary psychology research by Leda Cosmides and John Tooby, indicates that we tend to apply more accurate Bayesian reasoning when presented with probabilistic data in frequency form.
En el primer caso, se ofrece un esbozo de la perspectiva mantenida por Tooby y Cosmides (1992), la cual se considera una alternativa teorica y metodologica que puede ser vista como continuadora de la tradicion en ciencias sociales del proyecto inaugurado por los padres del positivismo.
Dutton retorna la tesis de Darwin y trata de desarrollarla a partir del marco conceptual de la psicologia evolucionista, que han impulsado teoricos como Leda Cosmides, John Tooby o Steven Pinker, entre otros muchos.
As Cosmides and Tooby have phrased this "Our modern skulls house a stone age mind" (Cosmides and Tooby 1997: 6).
A esta direccion apunta la teoria de los contratos sociales, defendida en trabajos como Fiddick, Cosmides y Tooby (2000) y que senala que los seres humanos disponemos de mecanismos mentales producto de nuestra evolucion que nos permiten enfrentarnos adecuadamente a situaciones sociales de intercambio y detectar, sin mayores dificultades, a las personas que no actuan apropiadamente en tales relaciones, es decir, a las personas que violan las normas o los acuerdos disfrutando de beneficios sin cumplir ningun requerimiento.