Corynebacterium diphtheriae


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium
References in periodicals archive ?
Efficient discrimination within a Corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method.
Efecto in vitro de diferentes concentraciones de extracto alcoholico de Caesalpinia spinosa (Molina) Kuntze, sobre la viabilidad de Corynebacterium diphtheriae.
Genotypic and phenotypic characteristics of Corynebacterium diphtheriae strains isolated from patients in Belarus during an epidemic period.
Rapid screening for toxigenic Corynebacterium diphtheriae by the polymerase chain reaction.
Outbreak investigation for toxigenic Corynebacterium diphtheriae wound infections in refugees from northeast Africa and Syria in Switzerland and Germany by whole genome sequencing.
Emergence and molecular characterisation of non-toxigenic tox gene-bearing Corynebacterium diphtheriae biovar mitis in the United Kingdom, 2003-2012.
Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.
Culture of a throat swab specimen was negative for Corynebacterium diphtheriae.
Multilocus sequence types of invasive Corynebacterium diphtheriae isolated in the Rio de Janeiro urban area, Brazil.
Rapid detection and molecular differentiation of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by LightCycler PCR.

Full browser ?