Corynebacterium diphtheriae


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Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium
References in periodicals archive ?
Efficient discrimination within a Corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method.
Buescher ES Diphtheria (Corynebacterium diphtheriae).
When referring to thermal death points, it is apparent that Corynebacterium diphtheriae can be destructed at the lowest temperature (58[degrees]C), while Salmonella typhimurium, Brucella melitensis, Mycobacterium tuberculosis and group A streptococci can all be destroyed at 62[degrees]C, if exposed to this temperature for a certain time span (ranging from 20-21 seconds for Corynebacterium diphtheriae to up to 135-144 seconds for group A streptococci).
Efecto in vitro de diferentes concentraciones de extracto alcoholico de Caesalpinia spinosa (Molina) Kuntze, sobre la viabilidad de Corynebacterium diphtheriae. Rev.
Pharyngeal or cutaneous diphtheria caused by toxigenic Corynebacterium diphtheriae and C.
An outbreak of nontoxigenic Corynebacterium diphtheriae infection: single bacterial clone causing invasive infection among Swiss drug users.
Screening for Corynebacterium diphtheriae and Corynebacterium ulcerans in patients with upper respiratory tract infections 2007-2008: a multicentre European study.
The return of Corynebacterium diphtheriae: the rise of non-toxigenic strains.
ulcerans infections can be clinically indistinguishable from toxigenic Corynebacterium diphtheriae infections.
(4) Other bacterial agents that occasionally cause pharyngitis and are reported when recovered include group B and C beta-hemolynic streptococci, Neisseria gonorrhoeae, Arcanobacterium haemolyticum, Corynebacterium diphtheriae, Chlamydia pneumoniae, and Mycoplasma spp.
Detection of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by a novel real-time PCR.
IHC using polyclonal antibodies for Corynebacterium diphtheriae showed rare epithelial staining in four of seven cases, although this test has unknown specificity.

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