Cortisporin


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Cortisporin

 [kor″tĭ-spor´in]
trademark for combination preparations of polymyxin b, neomycin sulfate, hydrocortisone, and (in some preparations) bacitracin zinc. Uses include topical preparations for dermatoses and ophthalmic and otic preparations for inflammatory conditions where there is actual or potential risk of bacterial infection.
References in periodicals archive ?
syrup, drops), Lanoxin (medicine for Heart issues), Folic Acid (for iron deficiency), Polyfax eye ointment, Cortisporin eye ointment, Motival tablets (tranquilizer), Kenacort Injection (anti-allergic), Migril tablets (for headache), Lomotil tablets, Gravinate (Anti-vomiting), Avil tablet, injection (anti-allergy), Syntocinon injection (for delivery cases), Tegral tablets (Mental issues), Trenalen tablets (anti-depression), Prolution depot (for maintenance of pregnancy) and some other routine medicines were found missing or present on enhanced rates.
A comparison of cortisporin and ciprofloxacin otic drops as prophylaxis against post-tympanostomy otorrhea.
In another small study, successful eradication of MRSA was achieved using a combination of oral trimethoprim-sulfamethoxazole plus topical gentamycin sulfate or polymyxin B sulfate-neomycin sulfate-hydrocortisone (Cortisporin) in 6 children (5 with prior tympanostomy tube placement and one with perforation of the tympanic membrane) who had failed either oral antibiotics or fluoroquinolone ear drops alone (Arch.
In another small study, successful eradication of MRSA was achieved using a combination of oral trimethoprim-sulfamethoxazole plus topical gentamycin sulfate or polymyxin B sulfate-neomycin sulfate-hydrocortisone (Cortisporin) in six children (five with prior tympanostomy tube placement and one with perforation of the tympanic membrane) who had failed either oral antibiotics or fluoroquinolone ear drops alone (Arch.
LOS ANGELES -- Cortisporin Otic did not cause ototoxicity and was cost effective when used for 5 days after ear tube placement surgery in children, according to a large retrospective review at a tertiary otologic center.
Berenholz and his colleagues at the Lippy Ear Group in Warren, Ohio, found no evidence of clinical ototoxicity in 500 children who received Cortisporin (neomycin, polymyxin B sulfates, and hydrocortisone otic solution) or a generic equivalent for 5 days after ventilation tube placement.
An analysis showed the total cost for using Cortisporin or a generic was $15,500 at $31 a bottle.
Overall, the data suggest that efficacy of Floxin and Ciprodex drops in treating acute otitis externa in children is greater than 90%, compared with about 80% for the generics such as Cortisporin (neomycin, polymyxin B sulfates, and hydrocortisone otic solution), and about 70% for astringents such as acetic acid, isopropyl alcohol, or hydrogen peroxide.
Clinical cure rates at day 18 were 90.9% after 7 days of Ciprodex (3-4 drops twice daily), compared with 83.9% after 7 days of Cortisporin (3-4 drops three times daily), while microbiologic eradication rates were 94.7% and 86%, respectively (Curr.
suggested that the two most common organisms associated with otitis externa--Pseudomonas aeruginosa and Staphylococcus aureus--appear to be developing resistance to Cortisporin but not to Floxin (South.
Younis cited laboratory studies in which Ciprodex Otic was superior to Cortisporin Otic in resolving acute otitis externa and eradicating bacteria, and was superior to ofloxacin in clinical efficacy against acute otitis media with tubal otorrhea (Pediatrics [online] 113[1], 2004; www.pediatrics.org/cgi/content/ full/113/1/e40; and Laryngoscope 113[12]:2116-22, 2003).
A comparison of cortisporin and ciprofloxacin drops as prophylaxis against post-tympanostomy otorrhea.