transcortin

(redirected from Cortisol binding globulin)

transcortin

 [trans″kor-tin]
an α-globulin that binds and transports biologically active, unconjugated cortisol in plasma.

trans·cor·tin

(tranz-kōr'tin),
An α2-globulin in blood that binds cortisol and corticosterone; the principal corticosteroid-binding protein in the plasma.

SERPINA6

A gene on chromosome 14q32.1 that encodes an alpha-globulin with corticosteroid-binding properties, which is the major transport protein for glucocorticoids and progestins in most vertebrates. SERPINA6 localises to a chromosomal region containing several closely related serine protease inhibitors, and may have evolved by duplication events.

trans·cor·tin

(trans-kōr'tin)
An α2-globulin in blood that binds cortisol and corticosterone; the principal corticosteroid-binding protein in the plasma.
Synonym(s): corticosteroid-binding globulin.
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References in periodicals archive ?
Pooley increased her hydrocortisone until her total estrogen dropped to 37, and her Cortisol binding globulin became normal.
The distribution of cortisol concentrations (nmol/L) relative to cortisol binding globulin concentrations (mg/L) in nonpregnant healthy females * and pregnant females **.
(3) Some women may not show signs of Cushing's syndrome despite increased cortisol levels because they may have increased cortisol binding globulin (CBG) levels or decreased sensitivity to cortisol.
High serum levels of Cortisol binding globulin (CBG or transcortin) often cause intracellular Cortisol deficiency.
Remissions were also associated with a decrease in elevated cortisol binding globulin into the normal range, which he thinks is 3.0 mg/dL or less.