Berberine, an orangish-yellow alkaloid found at high levels in the bark and root structures of plants including Oregon grape (Mahonia aquifolium), goldenseal (Hydrastis canadensis), barberry (Berberis vulgaris), and Chinese goldthread (Coptis chinensis
), has a broad and wide history of use.
Botanical name Family Collection site Coptis chinensis
One case report describes aspirated Coptis chinensis
, a Chinese herbal medicine, for 10 years .
Gegen Qinlian (GGQL) decoction, which is composed of Radix Puerariae (ge gen), Radix Scutellariae (huang qin), Coptis chinensis
Franch (huang lian), and Radix Glycyrrhizae Praeparata (zhi gan cao), has been addressed for its medicinal effect against DM for almost ten years .
For the bone marrow failure syndrome resulting from immune-mediated destruction of HSC, we modified DBT to prepare a derivative herb formula (DGBX) by adding Coptis chinensis
Franch (Coptidis rhizoma) for reinforcing the regulatory effect on aberrant immune response in the bone marrow of patients with AA.
Rhizoma Coptidis can be used for treatment of cardiovascular and neurodegenerative diseases ; Coptis chinensis
Franch extracts show good inhibitory activity for AChE in vitro .
Zhang et al., "Investigation of the differences between the "COLD" and "HOT" nature of Coptis chinensis
Franch and its processed materials based on animal's temperature tropism," SCIENCE CHINA Life Sciences, vol.
Chinese goldthread, Coptis chinensis
Franch., is an important medicinal plant in the Ranunculaceae.
GQ a Chinese medicinal herb decoction, including four quality assured herbs: Scutellaria baicalensis Georgi., Coptis chinensis
Franch., Pueraria lobata (Willd.) Ohwi., Glycyrrihiza uralensis Fisch., has been used as an efficient acute diarrhea medicine from the Eastern Han dynasty for about 2000 years (Li et al., 2004).
Berberine, an alkaloid isolated from a number of plants including Berberis vulgaris, Hydrastis canadensis, Coptis chinensis
and Mahonia aquifolium, has been used extensively for treating diarrhoea and gastrointestinal (GI) complaints for centuries, with recognised antimicrobial, anti-motility, anti-permeability and anti-secretory properties.
Draco supplies a 20% berberine extract from the TCM herb Coptis chinensis
and a Gynostemma extract (30% saponins).
It has been reported that the aqueous extracts of Coptis chinensis
(goldthread), Polygonum cuspidatum (Japanese knotweed), Cinnamomum cassia (cinnamon), Rheum officinale (Chinese rhubarb), Polygonum multiflorum, and Eugenia caryophyllata (clove) showed inhibitory effects on conidial germination of Oidium murrayae .