Eubacterium coprostanoligenes, a small gram-positive and cholesterol-reducing anaerobe, promotes the conversion of cholesterol to coprostanol
(Madden et al.
1990), analysis revealed the presence of stanols and stanones in high abundance including coprostanol
(5[beta]-cholestanol), epicoprostanol and coprostanone (5[beta]-cholestan-3-one).
and hydrocarbon distribution adjacent to a swage outfall.
1:45 POLYNUCLEAR AROMATIC HYDROCARBONS IN KEEGAN BAYOU, BILOXI, MS, USING COPROSTANOL
TO TRACK TRANSPORT
Of the 50 locations sampled in the study, Anne's Beach exhibited one of the highest concentrations of coprostanol
and cholesterol (indicators of human sewage).
Susan Glassmeyer, a research chemist in the National Exposure Research Laboratory, says what is needed is a "mass fingerprint" of 10-15 compounds, a mix of pollutants including drugs, bleaching agents, surfactants, compounds produced by the human body such as coprostanol
, and yes, caffeine.
is produced in the digestive tract of humans by the microbial hydrogenation of cholesterol (Rosenfield & Gallagher, 1964).
The enzyme reacts with cholesterol and converts it to coprostanol
, a sterol that passes through the body when consumed.
The researchers plotted the organic traces on the floor of a reconstructed house at Lejre in Denmark, noting areas enriched with coprostanol
and 24-ethylcoprostanol; compounds that could be directly associated with 'faecal biomarkers for herbivores'--or cowpats, as we mainstream archaeologists say.
And that change can be important, because unlike cholesterol, coprostanol
is not absorbed by the human body.
had even a lower relative intensity compared with cholesterol and, like lathosterol, has not been reported to be present in concentrations in serum that would alter the results obtained by the CDC Reference Method for cholesterol .
(5[Beta]-cholestan-3[Beta]-ol) in lagoonal sediments and mussels of Venice, Italy, Marine Pollution Bulletin 26(9): 501-7.