coproporphyrinogen oxidase

Also found in: Acronyms.

cop·ro·por·phy·rin·o·gen ox·i·dase

an enzyme that catalyzes a step in porphyrin biosynthesis, reacting coproporphyrinogen III and O2 to form protoporphyrinogen IX and 2CO2. A deficiency of this enzyme will result in hereditary coproporphyria.
References in periodicals archive ?
The association between genetic polymorphisms of coproporphyrinogen oxidase and an atypical porphyrinogenic response to mercury exposure in humans.
In patient B, erythrocyte PBGD, uroporphyrinogen-III synthase, and uroporphyrinogen decarboxylase as well as lymphocyte coproporphyrinogen oxidase, protoporphyrinogen oxidase, and ferrochelatase activities were additionally examined; all were within reference values.
The excessive urinary coproporphyrin excretion cannot be caused by an enzymatic deficiency, because coproporphyrinogen oxidase activity was within reference values.