thalassaemia

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thal·as·se·mi·a

, thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă)
Any of a group of inherited disorders of hemoglobin metabolism in which there is impaired synthesis of one or more of the polypeptide chains of globin; several genetic types exist, and the corresponding clinical picture may vary from barely detectable hematologic abnormality to severe and fatal anemia. People of Mediterranean, extraction are more often affected than others by this type of anemia.
Synonym(s): thalassaemia, thalassanaemia.
[G. thalassa, the sea, + haima, blood]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

thalassaemia

One of several hereditary abnormalities of synthesis of the globin chains of HAEMOGLOBIN leading to severe ANAEMIA. The disorder is common in the area surrounding the Mediterranean sea. When the abnormality is HETEROZYGOUS (thalassaemia minor), disability is minimal, but when HOMOZYGOUS (thalassaemia major), anaemia may be severe with breathlessness, jaundice, spleen enlargement and sometimes physical and mental retardation. Treatment is by blood transfusion and bone marrow transplantation. From the Greek words thelazia , the sea, and haima , blood.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

thal·as·se·mi·a

, thalassanemia (thal'ă-sē'mē-ă, -ă-să-nē'mē-ă)
Any of a group of inherited disorders of hemoglobin metabolism with impaired synthesis of one or more polypeptide chains of globin; several genetic types exist.
Synonym(s): thalassaemia, thalassanaemia.
[G. thalassa, the sea, + haima, blood]
Medical Dictionary for the Dental Professions © Farlex 2012