The Janssen Pharmaceutical Companies of Johnson & Johnson announced that the European Commission has approved the expanded use of ustekinumab for the treatment of adults with moderately to severely active ulcerative colitis, who have had an inadequate response with, lost response to, or were intolerant to either
conventional therapy or a biologic or have medical contraindications to such therapies.
By providing Smyraf[R] as a new therapeutic option, Astellas will contribute to treatment of rheumatoid arthritis patients with an inadequate response to
conventional therapy such as DMARDs.
Penicillamine Capsules USP are indicated in the treatment of Wilson's disease, cystinuria, and in patients with severe, active rheumatoid arthritis who have failed to respond to an adequate trial of
conventional therapy.
The research involved conducting animal-assisted therapy sessions for 19 adult participants alongside
conventional therapy sessions.
The study participants were allocated in two groups: Group A was given Treatment 1 as
conventional therapy and group B was supplemented with Vitamin D (50000 I.U) after every week for a period of one month (the serum Vitamin D levels were not sufficient (below 30ng/ml).8
Conventional therapy consisted of alternate use of 2 Tablet Betnesol 0.5mg dissolve in 10ml of bezy-dymaine chlorhexidine mouth wash and 4 to 5 drops of Nilstat taken 3 times a days.
In the study, Lu AF35700 did not show statistical superiority versus
conventional therapy on the primary endpoint (change in Total PANSS) in patients with treatment-resistant schizophrenia (TRS).
It's also a reminder that these attractive alternative therapies flourish when there is limited access to
conventional therapy, which can be truly expensive, difficult to sustain, or experimental.
(ii) Group B: patients in this group underwent
conventional therapy only.
Four patients received normal saline with conventional standard care, three patients received fibrin spray plus
conventional therapy, and four patients received
conventional therapy plus autologous mesenchymal stem cells delivered in fibrin spray at a dose of 1 x 106 cells per square centimeter of wound surface.
[63] tid + conventional treatment Intervention methods Outcome Author Controls measurement Tian [15]
Conventional therapy (1) (2) (3) (5) (flunarizine, nimodipine, hydroxyethylrutin, etc.) Zhang [16] Conventional antipressure (1) (2) & cerebral protection therapy Kang [17]
Conventional therapy (1) (4) (atorvastatin, aspirin) T.