The Janssen Pharmaceutical Companies of Johnson & Johnson announced that the European Commission has approved the expanded use of ustekinumab for the treatment of adults with moderately to severely active ulcerative colitis, who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy
or a biologic or have medical contraindications to such therapies.
By providing Smyraf[R] as a new therapeutic option, Astellas will contribute to treatment of rheumatoid arthritis patients with an inadequate response to conventional therapy
such as DMARDs.
Penicillamine Capsules USP are indicated in the treatment of Wilson's disease, cystinuria, and in patients with severe, active rheumatoid arthritis who have failed to respond to an adequate trial of conventional therapy
The research involved conducting animal-assisted therapy sessions for 19 adult participants alongside conventional therapy
The study participants were allocated in two groups: Group A was given Treatment 1 as conventional therapy
and group B was supplemented with Vitamin D (50000 I.U) after every week for a period of one month (the serum Vitamin D levels were not sufficient (below 30ng/ml).8 Conventional therapy
consisted of alternate use of 2 Tablet Betnesol 0.5mg dissolve in 10ml of bezy-dymaine chlorhexidine mouth wash and 4 to 5 drops of Nilstat taken 3 times a days.
In the study, Lu AF35700 did not show statistical superiority versus conventional therapy
on the primary endpoint (change in Total PANSS) in patients with treatment-resistant schizophrenia (TRS).
It's also a reminder that these attractive alternative therapies flourish when there is limited access to conventional therapy
, which can be truly expensive, difficult to sustain, or experimental.
(ii) Group B: patients in this group underwent conventional therapy
Four patients received normal saline with conventional standard care, three patients received fibrin spray plus conventional therapy
, and four patients received conventional therapy
plus autologous mesenchymal stem cells delivered in fibrin spray at a dose of 1 x 106 cells per square centimeter of wound surface.
 tid + conventional treatment Intervention methods Outcome Author Controls measurement Tian  Conventional therapy
(1) (2) (3) (5) (flunarizine, nimodipine, hydroxyethylrutin, etc.) Zhang  Conventional antipressure (1) (2) & cerebral protection therapy Kang  Conventional therapy
(1) (4) (atorvastatin, aspirin) T.