conserved sequence


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conserved sequence

a NUCLEOTIDE SEQUENCE in a DNA or RNA molecule or an AMINO ACID SEQUENCE in a PROTEIN that has remained largely unchanged during evolution; the sequence being very similar between many species. Examples include sequences in PROMOTERS, RIBOSOMAL RNA, and in proteins involved in DNA REPLICATION. See also CONSENSUS SEQUENCE.
References in periodicals archive ?
Sequences required for the activity of PTOX (IMMUTANS), a plastid terminal oxidase: in vitro and in planta mutagenesis of iron-binding sites and a conserved sequence that corresponds to Exon 8.
Such an alignment generates a sequence-similarity hierarchy in which the most closely conserved sequence is listed first, thereby identifying the organisms which were most likely growing in the students' houses.
Conserved sequence motifs, alignment, and secondary structure for the third domain of animal 12S rRNA.
To identify regions of conserved sequence characteristics, we downloaded pair-wise alignment data from the UCSC Genome Browser version Human/Cow (bosTau4), Mouse/Cow (bosTau4), and Human/Mouse (mm9) with pair-wise alignments.
Pro] gene to the central domain); the central domain (CD); and the conserved sequence block (CSB, from the CD to the tRN[A.
Hammerhead ribozymes, as based on the Haseloff and Gerlach model (Nature, 1988), consist of a catalytic core made up of a highly conserved sequence of 24 nucleotides that cleave substrate RNAs.
The mannose binding sites are based on conserved sequence QXDXNXVXY.
These reagents contain shorter highly conserved sequence regions improving assay specificity, and the probes are non-cleavable which allows post-PCR melt curve analysis.
Juvaris' universal influenza vaccine has demonstrated significant induction of immunity with a novel construct of M2e, which is a conserved sequence found on all influenza A strains.