consensus sequence

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consensus sequence

[kənsen′səs]
a sequence of nucleotides or amino acids similar or identical between regions of homology in different but related DNA, RNA, or protein sequence.

consensus sequence

a sequence of NUCLEOTIDES or AMINO ACIDS that is used to describe a number of related but not identical sequences. It is compiled by inserting the nucleotide occurring most often at each position in the real sequences.

sequence

the order in which monomers occur in polymeric molecules; the order of amino acids in a polypeptide chain or of nucleotides in nucleic acid.

autonomously replicating sequence
usually plasmids that replicate independently of chromosomal DNA.
coding s's
sections of DNA which code for the amino acids of a protein.
consensus sequence
a sequence of nucleotides that is always present in a large set of independently determined sequences. See also box.
enhancer sequence
in DNA transcription, an upstream cis-acting DNA sequence that enhances expression of a particular gene and forms part of a complex array of upstream sequences that control gene expression.
expressed s's
in eukaryotic pre-messenger RNA the noncoding sequences, also called intervening sequences or introns, are removed in the nucleus; the mRNA is transported to the cytoplasm where the exons are translated to a protein.
intervening sequence
see intron.
palindromic sequence
signal sequence
a collection of hydrophobic amino acid residues at the amino terminus of secretory or integrated membrane proteins that direct the protein to cell membranes, particularly endoplasmic reticulum where the proteins are modified, e.g. glycosylated, and the signal sequence is removed prior to secretion or integration of the protein into the lumen of the endoplasmic reticulum.
temporal sequence
in protein synthesis, is from the amino to the carboxyl end.
References in periodicals archive ?
List of heat shock elements deduced, their position and matching percent accuracy to the consensus sequence (in Red).
Consequently, there is a clear need for a NGS based HLA genotyping method and analytical pipeline that not only can generate accurate HLA genotyping information, but also generate an accurate, fully phased HLA consensus sequence for both genotyped alleles.
Serotype/specific consensus sequences of the HLA class/II restricted T/cell epitope at amino acid position 81/92 of the capsid protein.
Consensus sequence GQC, KGHYTEG, DNE AL and glycine rich sequences SLGGGTGSG MG are binding site for phosphoryl group of nucleotide and are observed in other nucleotide binding proteins (Figure 1) (22).
Consensus amino acid sequences of the PR and RT regions were created and then compared with the global subtype C and the global subtype B consensus sequences obtained from GenBank (2000).
Considering the first 300 amino acids in the RT gene, sequence alignment showed that the consensus sequences of the test viruses were identical to the global subtype C consensus, except at 2 positions (V60I and Q174K).
Herein, recombinant plasmids coding consensus sequences for M protein from genotypes A, D and F were constructed.
Putative consensus sequences for additional kinases such as GSK3, Cdk, CaMKII, and PKA have been identified.
Phylogenetic analysis was performed using the consensus sequences determined for each avian case in Virginia in combination with avian poxvirus core 4b gene sequence from isolates previously described in Europe and that of vaccinia virus.
The single-source and overall consensus sequences representing the SSU rRNA gene sequence of the amoebae from western LIS lobsters shared 99% nucleotide sequence identity to each other and demonstrated 98% or greater nucleotide sequence identity in nucleotide BLAST searches with SSU rRNA gene sequences of Neoparamoeba pemaquidensis strains.
Chromatograms from individual sequencing runs were trimmed, then assembled into consensus sequences in Sequencher (GeneCodes Corp.
In February 2004, MorphoSys obtained an additional United States patent covering the genetic constitution of synthetic, fully modular human antibody libraries based on in silico consensus sequences.