connexins

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con·nex·ins

(kŏ-neks'inz),
Complex protein assemblies; a group of six makes up a connexon.
See also: connexons.
References in periodicals archive ?
Connexins are trans-membrane proteins that have a role in communication and transferring of ions and small signaling molecules between cells.8 This locus is already been reported in Pakistani and Mediterranean families supporting that GJB2 is the main gene for inherited sensorineural deafness.9 More than 90 variants in GJB2 have been reported and meta-analysis in different ethnic group confirmed a strong association of GJB2 mutation with HL in different population.10
Connexin's involvement in the project led to it winning the Smart City Development of the Year award at the IoT Breakthrough Awards.
pattern of vascular connexin expression in atherosclerotic plaques.
Cornea Limbus Basal Suprabasal Basal Suprabasal cells cells cells cells CK3/CK12 ++ ++ - + CK19 - - + - CK5/CK14 +/- - + +/- Vimentine - - ++ + [alpha]-enolase + - ++ +/- Metallothionein - + +/- + Connexin 43 ++ + - + Connexin 50 ++ ++ - - Desmoglein-3 - + - + E-cadherin ++ ++ +/- ++ P-cadherin + - +/- - Integrin [alpha]9 - - ++ +/- Integrin [beta]1 + + + + + Integrin [alpha]6 ++ + +/- + ABCG2 - - ++ - ABCB5 - - + - E-cadherin ++ ++ +/- ++ P-cadherin +/- - +/- - [DELTA]Np63[alpha] - - ++ +/- C/EBP[delta] - - + - Bmi1 - - + - Notch 1 - - + - NGF-R TrkA + +/- + +/-
Hood, "Mutations in the connexin 26 gene (GJB2) among Ashkenazi jews with nonsyndromic recessive deafness," The New England Journal of Medicine, vol.
The connexins are structurally related proteins that assemble to form gap junctions which play an important role in cell-to-cell electrical communication and cardiac rhythmicity.
Hodgins, "Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium," Journal of Investigative Dermatology, vol.
Suzumura, "Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases," Frontiers in Cellular Neuroscience, vol.
Structural and functional diversity of connexin genes in the mouse and human genome.
Jobs generally last from December till April, Ski-jobs.co.uk Connexin
Connexin 26 mutations in hereditary non-syndromic sensorineural deafness.
However, with their topography and discovery being lumped with the gap junction field (i.e., connexin), they were thought for a long time to be more similar to connexin-based proteins.