congenital insensitivity to pain

(redirected from Congenital indifference to pain)

congenital insensitivity to pain

,

CIP

A rare defect in perception of pain in which children are born with an inherited sensory and autonomic neuropathy and a markedly reduced ability to perceive painful experiences, e.g., bone and joint injuries, lacerations, and abrasions.
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References in periodicals archive ?
Congenital indifference to pain is a rare syndrome, which characteristically features failure to exhibit aversion to or withdrawal from painful stimuli, despite not having neurological abnormalities in pain pathways (1).
The patient was given an electrophysiological impression of a normal study, and a clinical correlation for a diagnosis of congenital indifference to pain was suggested.
The terms congenital indifference to pain and congenital insensitivity to pain (CIP) were used interchangeably until 1970, when they were distinguished and described as two distinct syndromes (1).
The cases of congenital indifference to pain become evident at early childhood with frequent fractures, ulcers, and burns.
Small fiber neuropathy and congenital indifference to pain (the official name for the Pakistanis' pain-free condition) are just two of a handful of human pain disorders that have in the last decade been linked to malfunctioning [Na.sub.v]l.7.
Types of disease Main features of disease Type I Sensory radicular neuropathy Type II Congenital sensory neuropathy Type III Familial dysautonomia Type IV Congenital insensitivity to pain with anhidrosis Type V Congenital indifference to pain In this group of diseases, Type I is the most common dominantly inherited disorder which primarily affects sensory neurons.
Still more unfortunate are people born with a rare disorder, so-called "congenital indifference to pain," who never experience pain at all.

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