The low-pain condition is called congenital analgesia
and has been connected to a couple of other genetic mutations as well, but the studied family has a unique set of symptoms.
takes place as the result of a defect in the gene called "SCN9A.
Gardell's Steve suffers from congenital analgesia
in "This Hurts,'' so when Molly Buckey's Marvalyn accidently smacks him with an ironing board, he can't feel it.
Somewhat of a loner, she finally recruits Kaya, suffering from congenital analgesia
and the inability to feel physical pain; Kit, mourning the death of his girlfriend; Ellen, a drug addict; and Thomas, who has nightmares about his life as a child soldier in the Liberian militia.
The movie does feature graphic sex and several bloody fight scenes featuring a vicious henchman who has congenital analgesia
- a rare condition that means he suffers no pain.