GIF

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macrophage migration inhibitory factor

A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration.

Gene
MMIF is encoded by MIF on chromosome 22q11.23.

Activities
Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.
 
Mechanism
Increases intracellular cAMP, polymerises microtubules, stops macrophage progression.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
MediaRing will also bundle CompuServe software in its MediaRing Talk software packages distributed with magazines and through retail outlets.
Source: CompuServe, Inc., Columbus, OH, 800/554-4095.
It was as if CompuServe, in preparing to welcome the new year, was also welcoming a new era, an era in which individuals and governments, journalists, and Internet service providers will be trying to figure out an international communications network that can slip information across borders in ways smugglers of old only could imagine.
In addition to the major on-line service providers such as America Online, CompuServe and Prodigy, there are specialized Internet providers, such as The Pipeline.
PRODIGY, CompuServe, and the other online companies still are too awkwardly designed and too "techy" to capture a mass market.
Among these are forums that will allow users to participate in real-time discussions with other members and to archive their discussions in a manner similar to that used in CompuServe forums.
Other forums and services on Compuserve deal with CD-ROM products.
I went into the files of direct mail packages and retrieved mailings from America Online, CompuServe and Prodigy.
Prodigy and CompuServe allow unlimited use of basic services for fees of $14.95 and $8.95 per month respectively.
The main difference between the Internet and other online services like CompuServe and Prodigy is that these latter services are run by privately owned companies, each with its own protocol, bulletin boards and software.
David DuBuisson Greensboro News & Record CompuServe: 71175,25