GIF

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macrophage migration inhibitory factor

A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration.

Gene
MMIF is encoded by MIF on chromosome 22q11.23.

Activities
Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.
 
Mechanism
Increases intracellular cAMP, polymerises microtubules, stops macrophage progression.

GIF,

References in periodicals archive ?
Each file and message in the Forum and in most Compuserve forums have a series of keywords prepared by the file or message contributor.
Vance, who heads up the KTR Environmental Services, finds the electronic access very helpful and calls CompuServe a powerful research tool.
Through this new service, MHS users can access an MHS hub on CompuServe through hundreds of domestic and international locations," said Tom White, president of Action Technologies.
One potential problem is the transition of Parti to CompuServe is the differences in the way the companies are perceived to operate their networks.
In addition, he said there's no guarantee the CompuServe members would become AOL members.
Massey declined to say whether CompuServe was going to be split up.
com and CompuServe Entertainment Channels, visitors can find a host of "Glory Days" interactive content and links to the sweepstakes in a special area dedicated to the show.
We will significantly step up marketing efforts for CIS within the next month,'' said Bob Massey, president and chief executive officer of CompuServe.
Rena's advice column can be found on CompuServe by clicking on the Celebrity Channel and then by clicking the "Ask Rena" button in the right column or just by using Keyword: "AskRena.
Neither company would disclose how much CompuServe, which is majority owned by H&R Block, was paying to license the Normandy software.
Deciding to flow with the relentless tide of the Internet rather than fight it, CompuServe Inc.