cytochrome c oxidase

(redirected from Complex IV)

cy·to·chrome c ox·i·dase

(sī'tō-krōm oks'i-dās),
A cupriferous cytochrome of the a type that catalyzes the oxidation of four molecules of ferrocytochrome c by molecular oxygen to produce four molecules of ferricytochrome c and 2H2O. A part of Complex IV of the respiratory chain. A deficiency of one or more of the polypeptides of this complex results in neuronal loss in the brain leading to psychomotor retardation and neurodegenerative disease.
References in periodicals archive ?
H2S is a readily water-soluble gas, which at higher concentrations becomes toxic by binding to and inhibiting cytochrome C oxidase in complex IV of the electron transport chain, the last complex in the chain prior to ATP synthesis.
Complex I, complex II, complex IV, complex I and IV, complex I, III, and IV, complex I, IV, and V, and complex I, III, IV, and V deficiency or normal respiratory chain activity has been previously described in KSS.
3]-insensitive portion of stimulation was used to indicate complex IV dependent respiration.
PMEX, the only multi-commodity futures exchange in the country, has relocated its office premises to the new state-of-the-art building, Bahria Complex IV, Karachi.
The chain terminates at complex IV and the electrons are accepted by an oxygen molecule to form water.
These include drug-related side effects associated with morphine or hydromorphone, complications associated with IV delivery, and medication delivery errors typically associated with misprogramming of the complex IV PCA pumps.
The primary interventions included initiation of bar code scanning of medication vials and IV bags, improvement of work flow processes in the IV room, and elimination of manual order entry when producing complex IV solutions, lead author Dr.
The determination of the mitochondrial respiratory chain in the muscle homogenate showed a partial deficiency of complex III and a slightly diminished complex IV (Table I).
Complex III shuttles the electron to complex IV, and under controlled circumstances oxygen is reduced to form water Energy from the passage of electrons is used to transfer protons from the matrix to the intermembrane space.
l] complex;ferrocytochrome c oxidoreductase; coenzyme Q; cytochrome c reductase Complex IV = cytochrome oxidase; terminal oxidase; ferrocytochrome c; oxygen oxidoreductase; cytochrome c oxidase.
Full browser ?