androgen insensitivity syndrome

(redirected from Complete androgen insensitivity)
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androgen

 [an´dro-jen]
any steroid hormone that promotes male secondary sex characters. The two main androgens are androsterone and testosterone. Called also androgenic hormone. adj., adj androgen´ic. 

The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
androgen insensitivity syndrome complete androgen resistance.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

an·dro·gen re·sis·tance syn·dromes

a class of disorders associated with 5α-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5α-reductase, Reifenstein syndrome, infertile male syndrome, testicular feminization syndrome.
Farlex Partner Medical Dictionary © Farlex 2012

androgen insensitivity syndrome

n.
An inherited condition in which the body cells are completely or partially unable to respond to androgens, resulting, in the complete form, in a person with an XY karyotype developing typical female external genitalia but usually no uterus, a short vagina, and undescended or partially descended testes. People with mild or partial forms are infertile and have a variety of phenotypes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

an·dro·gen re·sis·tance syn·dromes

(an'drŏ-jen rĕ-zis'tăns sin'drōmz)
A class of disorders associated with 5α-steroid reductase deficiency, testicular feminization, and related disorders.
Compare: Reifenstein syndrome, testicular feminization syndrome
Synonym(s): androgen insensitivity syndrome.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Mutations of the androgen receptor gene in patients with complete androgen insensitivity. Hum Mutat 1997;9:57-61.
CAIS: complete androgen insensitivity syndrome, PAIS: partial androgen insensitivity syndrome, F: female, M: male, NTD: N-terminal domain, DBD: DNA-binding domain, LBD: ligand-binding domain, AIS: androgen insensitivity syndromes Supplemental Table 1.
DISCUSSION: Complete Androgen insensitivity syndrome (CAIS) was initially described in 1953 and has an incidence of 1: 2000 to 1: 64,000(2) and accounts for 10% of cases of primary amenorrhoea (3).They present either with inguinal hernias, or labial masses, primary amenorrhoea during adolescence, primary infertility after marriage.
The subjects of this two-part documentary suffered from conditions such as Klinefelter's Syndrome or Complete Androgen Insensitivity Syndrome, or they had both male and female physical/ psychological characteristics.
TORONTO -- Teenagers with complete androgen insensitivity syndrome need to be told that they are at high risk for sexual dysfunction, Dr.
TORONTO-- Teenagers with complete androgen insensitivity syndrome need to be told that they are at high risk for sexual dysfunction, Dr.
Mutations in AR gene disrupt function of Androgen receptor, such as missense amino acid substitutions, leading to diminished spermatogenesis and enhanced feminization of individual, resulting in complete androgen insensitivity syndrome.4
Two of them were reported to have complete androgen insensitivity syndrome whereas the other one had partial androgen insensitivity syndrome.
Complete androgen insensitivity syndrome: long-term medical, surgical, and psychosexual outcome.
In Complete Androgen Insensitivity syndrome (CAIS) the complete female appearance at birth usually masks the condition completely and the infants are raised without any doubt as girls.
In case of congenital hernias we need to rule out intersex syndromes especially in cases of bilateral inguinal hernias which is usually associate with complete androgen insensitivity syndrome (CAIS) (6).
This failure of virilization can be either complete androgen insensitivity syndrome (CAIS) or partial androgen insensitivity syndrome (PAIS), depending on the amount of residual receptor function.

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